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dTDP-4-dehydrorhamnose reductase

Summary

Gene Symbol

rfbD

Organism

Escherichia coli str. K-12 substr. MG1655

External Links

NCBI Gene: 947117
PubChem: 947117

Annotation

Keyword

Carbohydrate metabolism
Lipopolysaccharide biosynthesis
Magnesium
Metal-binding
NAD
NADP
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P37760	dTDP-4-keto-L-rhamnose reductase dTDP-6-deoxy-L-lyxo-4-hexulose reductase dTDP-6-deoxy-L-mannose dehydrogenase dTDP-L-rhamnose synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
O antigen biosynthetic process	EXP IEA	7512872 7517391
extracellular polysaccharide biosynthetic process	IBA ISS
lipopolysaccharide biosynthetic process	IEA ISS
dTDP-rhamnose biosynthetic process	IBA IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

extracellular polysaccharide metabolic process [inference]

extracellular polysaccharide biosynthetic process

O antigen metabolic process [inference]

O antigen biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

liposaccharide metabolic process [inference]

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

extracellular polysaccharide metabolic process [inference]

extracellular polysaccharide biosynthetic process

O antigen metabolic process [inference]

O antigen biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

liposaccharide metabolic process [inference]

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

extracellular polysaccharide metabolic process [inference]

extracellular polysaccharide biosynthetic process

O antigen metabolic process [inference]

O antigen biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate derivative metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

liposaccharide metabolic process [inference]

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

dTDP-rhamnose metabolic process [inference]

dTDP-rhamnose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

dTDP-rhamnose biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IBA IDA	18304323

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
oxidoreductase activity	IEA
dTDP-4-dehydrorhamnose reductase activity	IBA IEA ISS
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

dTDP-4-dehydrorhamnose reductase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:21796

dTDP-β-L-rhamnose + NADP⁺

H⁺ + NADPH + dTDP-4-dehydro-β-L-rhamnose

Enzyme

1.1.1.133

PMID

15020741

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements