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peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA

Summary

Gene Symbol

mrcA

Organism

Escherichia coli str. K-12 substr. MG1655

External Links

NCBI Gene: 947907
KEGG Gene ID: eco:b3396
PubChem: 947907

Annotation

Keyword

Antibiotic resistance
Carboxypeptidase
Cell inner membrane
Cell wall biogenesis/degradation
Direct protein sequencing
Glycosyltransferase
Multifunctional enzyme
Peptidoglycan synthesis
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P02918

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
peptidoglycan biosynthetic process	IBA IDA IEA NAS	16840781 31915748
proteolysis	IEA
response to antibiotic	IDA IEA IGI	345275 7006606
regulation of cell shape	IEA IGI NAS	31915748 7007327 9324260
cell wall organization	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

protein metabolic process [inference]

proteolysis

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

protein metabolic process [inference]

proteolysis

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

protein metabolic process [inference]

proteolysis

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall organization or biogenesis [inference]

cell wall organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

external encapsulating structure organization [inference]

cell wall organization

response to stimulus [inference]

response to chemical [inference]

response to antibiotic

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of biological quality [inference]

regulation of cell shape

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA NAS	31915748
outer membrane-bounded periplasmic space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

periplasmic space [inference]

outer membrane-bounded periplasmic space

Displaying entries **1 - 5** of 7 in total

1

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GO Term	Evidence Code	PMID
protein binding	IPI	21183073 21183074 22606933 32009249 33144379
serine-type carboxypeptidase activity	RCA	3882429
peptidoglycan glycosyltransferase activity	IBA IDA IEA	16840781 7006606
serine-type D-Ala-D-Ala carboxypeptidase activity	IDA IEA	16840781 26370943 7006606
penicillin binding	IDA IEA	330236 345275