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3-keto-L-gulonate-6-phosphate decarboxylase SgbH

Summary

Gene Symbol

sgbH

Organism

Escherichia coli str. K-12 substr. MG1655

External Links

NCBI Gene: 948098
PubChem: 948098

Annotation

Keyword

Carbohydrate metabolism
Decarboxylase
Magnesium
Metal-binding
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P37678	3-dehydro-L-gulonate-6-phosphate decarboxylase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
L-ascorbic acid catabolic process	IBA
carbohydrate catabolic process	IEP	10913096
'de novo' pyrimidine nucleobase biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

organonitrogen compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

catabolic process [inference]

cellular catabolic process [inference]

vitamin catabolic process [inference]

water-soluble vitamin catabolic process [inference]

L-ascorbic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

heterocycle catabolic process [inference]

lactone catabolic process [inference]

L-ascorbic acid catabolic process

small molecule catabolic process [inference]

vitamin catabolic process [inference]

water-soluble vitamin catabolic process [inference]

L-ascorbic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

monosaccharide catabolic process [inference]

L-ascorbic acid catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process

monosaccharide catabolic process [inference]

L-ascorbic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

organic cyclic compound catabolic process [inference]

lactone catabolic process [inference]

L-ascorbic acid catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

organonitrogen compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular catabolic process [inference]

vitamin catabolic process [inference]

water-soluble vitamin catabolic process [inference]

L-ascorbic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

heterocycle catabolic process [inference]

lactone catabolic process [inference]

L-ascorbic acid catabolic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

heterocycle catabolic process [inference]

lactone catabolic process [inference]

L-ascorbic acid catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

lactone catabolic process [inference]

L-ascorbic acid catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

monosaccharide catabolic process [inference]

L-ascorbic acid catabolic process

carbohydrate catabolic process

monosaccharide catabolic process [inference]

L-ascorbic acid catabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

monosaccharide catabolic process [inference]

L-ascorbic acid catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

water-soluble vitamin catabolic process [inference]

L-ascorbic acid catabolic process

vitamin catabolic process [inference]

water-soluble vitamin catabolic process [inference]

L-ascorbic acid catabolic process

small molecule catabolic process [inference]

vitamin catabolic process [inference]

water-soluble vitamin catabolic process [inference]

L-ascorbic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

monosaccharide catabolic process [inference]

L-ascorbic acid catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

monosaccharide catabolic process [inference]

L-ascorbic acid catabolic process

carbohydrate catabolic process

monosaccharide catabolic process [inference]

L-ascorbic acid catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

lactone catabolic process [inference]

L-ascorbic acid catabolic process

organic cyclic compound catabolic process [inference]

lactone catabolic process [inference]

L-ascorbic acid catabolic process

organic cyclic compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

organonitrogen compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

organic substance catabolic process [inference]

carbohydrate catabolic process

monosaccharide catabolic process [inference]

L-ascorbic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

organic cyclic compound catabolic process [inference]

lactone catabolic process [inference]

L-ascorbic acid catabolic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

organonitrogen compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular catabolic process [inference]

vitamin catabolic process [inference]

water-soluble vitamin catabolic process [inference]

L-ascorbic acid catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

L-ascorbic acid catabolic process

heterocycle catabolic process [inference]

lactone catabolic process [inference]

L-ascorbic acid catabolic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

heterocycle catabolic process [inference]

lactone catabolic process [inference]

L-ascorbic acid catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process [inference]

'de novo' pyrimidine nucleobase biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid catabolic process

lactone catabolic process [inference]

L-ascorbic acid catabolic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
orotidine-5'-phosphate decarboxylase activity	IEA
carboxy-lyase activity	IEA
metal ion binding	IEA
protein binding	IPI	15690043
3-dehydro-L-gulonate-6-phosphate decarboxylase activity	IBA IDA IEA	11741871

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

H⁺ + 3-dehydro-L-gulonate 6-phosphate

CO₂ + L-xylulose 5-phosphate

Enzyme

4.1.1.85

PMID

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024