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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

alpha-galactosidase

Summary

Gene Symbol

melA

Organism

Escherichia coli str. K-12 substr. MG1655

External Links

NCBI Gene: 948636
PubChem: 948636

Annotation

Keyword

Carbohydrate metabolism
Direct protein sequencing
Glycosidase
Manganese
Metal-binding
NAD
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P06720	Melibiase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
melibiose catabolic process	IMP	4877127

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

melibiose catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

melibiose metabolic process [inference]

melibiose catabolic process

disaccharide catabolic process [inference]

melibiose catabolic process

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

melibiose catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

melibiose catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

melibiose metabolic process [inference]

melibiose catabolic process

disaccharide catabolic process [inference]

melibiose catabolic process

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

melibiose catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

melibiose catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

melibiose catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IDA	2159786
cytosol	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying entries **6 - 10** of 10 in total

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1

2
GO Term	Evidence Code	PMID
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA
hydrolase activity, acting on glycosyl bonds	IEA
manganese ion binding	IDA	5329906
metal ion binding	IEA
NAD+ binding	IDA	5543331

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds

hydrolase activity, hydrolyzing O-glycosyl compounds

galactosidase activity [inference]

alpha-galactosidase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding [inference]

NAD+ binding

ion binding [inference]

anion binding [inference]

NAD+ binding

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

manganese ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding [inference]

NAD+ binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

H₂O + a globoside Gb3Cer (d18:1(4E))

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + D-galactose

Enzyme

3.2.1.22

PMID

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025