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Guidelines

MIRAGE

KDO transferase

Summary

Gene Symbol

waaA

Organism

Escherichia coli str. K-12 substr. MG1655

External Links

NCBI Gene: 949048
PubChem: 949048

Annotation

Keyword

Cell inner membrane
Lipopolysaccharide biosynthesis
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P0AC75	Bifunctional Kdo transferase Kdo-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
lipopolysaccharide biosynthetic process	IEA
lipopolysaccharide core region biosynthetic process	IEA
lipid A biosynthetic process	IMP	7499229
lipid A biosynthetic process	IBA
Kdo2-lipid A biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

oligosaccharide biosynthetic process [inference]

lipopolysaccharide core region biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

glycolipid biosynthetic process [inference]

lipooligosaccharide biosynthetic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process [inference]

lipopolysaccharide core region biosynthetic process

lipopolysaccharide core region metabolic process [inference]

lipopolysaccharide core region biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

oligosaccharide biosynthetic process [inference]

lipopolysaccharide core region biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

fatty acid derivative metabolic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

fatty acid derivative biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process [inference]

lipopolysaccharide core region biosynthetic process

lipopolysaccharide core region metabolic process [inference]

lipopolysaccharide core region biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

oligosaccharide biosynthetic process [inference]

lipopolysaccharide core region biosynthetic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

fatty acid derivative metabolic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

fatty acid derivative biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

glycolipid biosynthetic process [inference]

lipooligosaccharide biosynthetic process [inference]

lipooligosaccharide metabolic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

lipooligosaccharide biosynthetic process [inference]

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

oligosaccharide biosynthetic process [inference]

lipopolysaccharide core region biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

glycolipid biosynthetic process [inference]

lipooligosaccharide biosynthetic process [inference]

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

dicarboxylic acid biosynthetic process [inference]

Kdo2-lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

Kdo2-lipid A metabolic process [inference]

Kdo2-lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	RCA	27510400
plasma membrane	IDA	1577828
plasma membrane	IBA
plasma membrane	IEA
membrane	IDA	2651435

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
transferase activity	IDA	1577828 2651435
transferase activity	IBA
transferase activity	IEA
glycosyltransferase activity	IEA
Kdo transferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

Kdo transferase activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

an α-Kdo-(2→6)-lipid IV_A + CMP-3-deoxy-β-D-manno-octulosonate

H⁺ + an α-Kdo-(2→4)-α-Kdo-(2→6)-lipid IV_A + CMP

Enzyme

2.4.99.13

PMID

a lipid IV_A + CMP-3-deoxy-β-D-manno-octulosonate

H⁺ + an α-Kdo-(2→6)-lipid IV_A + CMP

Enzyme

2.4.99.12

PMID

lipid IV_A (E. coli) + CMP-3-deoxy-β-D-manno-octulosonate

H⁺ + α-Kdo-(2→6)-lipid IV_A (E. coli) + CMP

Enzyme

2.4.99.12

PMID

α-Kdo-(2→6)-lipid IV_A (E. coli) + CMP-3-deoxy-β-D-manno-octulosonate

H⁺ + α-Kdo-(2→4)-α-Kdo-(2→6)-lipid IV_A (E. coli) + CMP

Enzyme

2.4.99.13

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007590
Gene Name: 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase)

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.1

Last updated: April 7, 2025