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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase with thrombospondin type 1 motif 4
Summary
- Gene Symbol
-
- ADAMTS4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| O75173 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| extracellular matrix disassembly | ||
| extracellular matrix organization | ||
| skeletal system development |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| nuclear speck | ||
| collagen-containing extracellular matrix | ||
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| zinc ion binding | ||
| protease binding | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- thrombospondin
- Functional Category
-
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
| Gene Ontology |
|---|
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 41887 | FB:FBgn0286071 | |||
| 66015 | RGD:621242 | RATNO07479 | ||
| 177850 | WB:WBGene00001650 | |||
| 240913 | MGI:1339949 | MOUSE30178 | ||
| 286806 | BOVIN25529 | |||
| 457453 | 9598_0:0002ef | PANTR22807 | ||
| 488651 | CANLF14413 | |||
| 719927 | MACMU24348 | |||
| 100008765 | RABIT03178 | |||
| 100032755 | MONDO11793 |
