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GTP binding protein 1

Summary

Gene Symbol

GTPBP1

Organism

Homo sapiens (human)

External Links

NCBI Gene

9567

KEGG Gene ID

PubChem

9567

Alliance of Genome Resources

HGNC:4669

Annotation

Keyword

3D-structure
Cytoplasm
GTP-binding
Hydrolase
Intellectual disability
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
O00178

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
cytoplasmic translation	IDA
translational elongation	IBA
immune response	TAS
signal transduction	TAS
GTP metabolic process	ISS

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction

metabolic process [inference]

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

GTP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

GTP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

GTP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

GTP metabolic process

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

cytoplasmic translation

translational elongation

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance

macromolecule biosynthetic process [inference]

translation [inference]

cytoplasmic translation

translational elongation

protein metabolic process [inference]

translation [inference]

cytoplasmic translation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

RNA surveillance

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

GTP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

GTP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

GTP metabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

RNA surveillance

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

RNA surveillance

protein metabolic process [inference]

translation [inference]

cytoplasmic translation

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

GTP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

GTP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

GTP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

GTP metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

GTP metabolic process

response to stimulus [inference]

immune response

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

regulation of cellular process [inference]

signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of mRNA catabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of mRNA catabolic process

regulation of mRNA catabolic process [inference]

positive regulation of mRNA catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of mRNA catabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasmic exosome (RNase complex)	ISS
cytoplasmic exosome (RNase complex)	IEA
cytoplasm	IEA
cytosol	ISS
cytosol	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

exoribonuclease complex [inference]

exosome (RNase complex) [inference]

cytoplasmic exosome (RNase complex)

cellular anatomical structure [inference]

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
tRNA binding	IDA
RNA binding	HDA
translation elongation factor activity	IDA
translation elongation factor activity	IBA
GTPase activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

translation factor activity [inference]

translation elongation factor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Mus musculus	14904	MGI:109443

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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