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MIRAGE
CD40 molecule
Summary
- Gene Symbol
-
- CD40
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Immunity
- Proteomics identification
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P25942 |
|
| A0A8Q3SI60 |
|
| A0A0S2Z349 |
|
| Q6P2H9 |
|
| A0A0S2Z3C7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| immune response-regulating cell surface receptor signaling pathway | ||
| intracellular calcium ion homeostasis | ||
| inflammatory response | ||
| receptor signaling pathway via JAK-STAT | ||
| B cell mediated immunity |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane | ||
| cell surface | ||
| CD40 receptor complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| antigen binding | ||
| protein binding | ||
| enzyme binding | ||
| protein domain specific binding | ||
| ubiquitin protein ligase binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- tumor necrosis factor receptor superfamily
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| TNFR/NGFR cysteine-rich region |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050745 | diffuse large B-cell lymphoma | |
| DOID:0050873 | follicular lymphoma | |
| DOID:0060023 | immunodeficiency with hyper IgM type 3 | |
| DOID:0060060 | non-Hodgkin lymphoma | |
| DOID:12361 | Graves' disease | |
| DOID:13378 | Kawasaki disease | |
| DOID:1909 | melanoma | |
| DOID:2377 | multiple sclerosis | |
| DOID:2841 | asthma | |
| DOID:2959 | hyperimmunoglobulin syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 958 | Xenbase:XB-GENE-5963241 | ||
| 21939 | Xenbase:XB-GENE-5963241 | MOUSE34040 | |
| 171369 | RATNO26374 | ||
| 286849 | BOVIN05394 | ||
| 397395 | PIGXX11881 | ||
| 403469 | CANLF09617 | ||
| 443232 | SHEEP04779 | ||
| 707749 | MACMU01844 | ||
| 100034049 | HORSE20711 | ||
| 100220945 | TAEGU12193 |
