CD44 molecule (IN blood group)

Summary
Gene Symbol
  • CD44
Aliases
  • CD44R
  • CDw44
  • CSPG8
  • ECM-III
  • H-CAM
  • HCELL
  • HUTCH-1
  • HUTCH-I
  • Hermes-1
  • IN
  • In(Lu) related-p80
  • MC56
  • PGP-1
  • Pgp1
  • chondroitin sulfate proteoglycan 8
  • extracellular matrix receptor-III
  • hematopoietic cell E- and L-selectin ligand
  • homing cell adhesion molecule
  • phagocyte glycoprotein 1
Organism
Homo sapiens (human)
External Links
NCBI Gene
960
HGNC
1681
KEGG Gene ID
hsa:960
PubChem
960
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Blood group antigen
  • Cell adhesion
  • Cell membrane
  • Cell projection
  • Direct protein sequencing
  • Disulfide bond
  • Phosphoprotein
  • Proteoglycan
  • Receptor
  • Reference proteome
  • Secreted
  • Signal
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
P16070
  • CDw44
  • Epican
  • Extracellular matrix receptor III
  • GP90 lymphocyte homing/adhesion receptor
  • HUTCH-I
  • Heparan sulfate proteoglycan
  • Hermes antigen
  • Hyaluronate receptor
  • Phagocytic glycoprotein 1
  • Phagocytic glycoprotein I
Gene Ontology (GO)
GO Hierarchy
Human Protein Atlas
ENSG00000026508

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K06256
Name
CD44 antigen
References
Disease
Disease Ontology
Displaying entries 41 - 50 of 750 in total
DO ID Disease Name Source
DOID:0060873 isolated growth hormone deficiency type IA
DOID:0060874 isolated growth hormone deficiency type IB
DOID:0060875 isolated growth hormone deficiency type III
DOID:0060891 Parkinson's disease 19A
DOID:0060895 Parkinson's disease 4
DOID:0060896 Parkinson's disease 23
DOID:0070161 hereditary sensory and autonomic neuropathy type 2
DOID:0070324 systemic Epstein-Barr virus positive T-cell lymphoma of childhood
DOID:0070329 mitochondrial DNA depletion syndrome
DOID:0080144 childhood acute lymphocytic leukemia
Ortholog
Displaying entries 51 - 52 of 52 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
103749501 NANGA09876
116445020 CORMO23825

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024