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1,3-beta-D-glucan synthase

Summary

Gene Symbol

FKS1

Organism

Coccidioides posadasii str. Silveira

External Links

NCBI Gene: 9690981
KEGG Gene ID: cpw:CPC735_047360
PubChem: 9690981

Annotation

Keyword

Glycosyltransferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
C5PFR3	1,3-beta-D-glucan-UDP glucosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
fungal-type cell wall polysaccharide biosynthetic process	IEA	30032202
(1->3)-beta-D-glucan biosynthetic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

cell wall polysaccharide metabolic process [inference]

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

fungal-type cell wall polysaccharide metabolic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

glucan metabolic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan metabolic process [inference]

(1->3)-beta-D-glucan metabolic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

cell wall polysaccharide metabolic process [inference]

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

fungal-type cell wall polysaccharide metabolic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

glucan metabolic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan metabolic process [inference]

(1->3)-beta-D-glucan metabolic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

cell wall polysaccharide metabolic process [inference]

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

fungal-type cell wall polysaccharide metabolic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

glucan metabolic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan metabolic process [inference]

(1->3)-beta-D-glucan metabolic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

cell wall macromolecule metabolic process [inference]

cell wall polysaccharide metabolic process [inference]

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

fungal-type cell wall polysaccharide metabolic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell wall polysaccharide biosynthetic process [inference]

fungal-type cell wall polysaccharide biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
1,3-beta-D-glucan synthase complex	IEA	22301074

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

1,3-beta-D-glucan synthase complex

catalytic complex [inference]

transferase complex [inference]

1,3-beta-D-glucan synthase complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
1,3-beta-D-glucan synthase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

UDP-glucosyltransferase activity [inference]

1,3-beta-D-glucan synthase activity

hexosyltransferase activity [inference]

glucosyltransferase activity [inference]

UDP-glucosyltransferase activity [inference]

1,3-beta-D-glucan synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

synthase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
(1->3)-beta-D-glucan biosynthetic process
transferase activity

Displaying **all 2** entries
InterPro
1,3-beta-glucan synthase component FKS1-like, domain-1
Glycosyl transferase, family 48

KEGG BRITE Database

Orthology

K00706

Name

1,3-beta-glucan synthase [EC:2.4.1.34]

References

7565718

Rhea

UDP-α-D-glucose

H⁺ + UDP

Enzyme

2.4.1.34

PMID

14245356

Ortholog

Displaying **all 10** entries
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Coccidioides immitis RS	4566833	246410_0:00259a
Uncinocarpus reesii 1704	8438110	336963_0:0016d6
Blastomyces gilchristii SLH14081	8508237	559298_0:000124
Paracoccidioides lutzii Pb01	9096177	502779_0:001350
Microsporum canis CBS 113480	9230500	554155_0:001720
Trichophyton benhamiae CBS 112371	9521602	663331_0:000c7a
Nannizzia gypsea CBS 118893	10031632	535722_0:001f13
Trichophyton rubrum CBS 118892	10373887	559305_0:001e60
Paracoccidioides brasiliensis Pb18	22587743	502780_0:0012d4
Arthroderma uncinatum	54305188	74035_0:000050

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024