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translocation associated membrane protein 2

Summary

Gene Symbol

TRAM2

Organism

Homo sapiens (human)

External Links

NCBI Gene

9697

PubChem

9697

Alliance of Genome Resources

HGNC:16855

Annotation

Keyword

Glycoprotein
Reference proteome
Translocation
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q15035
A0A024RD84

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
collagen biosynthetic process	IMP	14749390
SRP-dependent cotranslational protein targeting to membrane, translocation	IEA
protein insertion into ER membrane	IBA IDA	27499293

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

collagen biosynthetic process

collagen metabolic process [inference]

collagen biosynthetic process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane

transmembrane transport [inference]

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

transmembrane transport [inference]

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

protein transmembrane transport [inference]

intracellular protein transmembrane transport [inference]

SRP-dependent cotranslational protein targeting to membrane, translocation

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	14749390

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Translocating chain-associated membrane protein

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ceramide biosynthetic process
sphingosine N-acyltransferase activity

Displaying 1 entry
InterPro
TRAM/LAG1/CLN8 homology domain

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	31042	FB:FBgn0040340
Mus musculus	170829	MGI:1924817	MOUSE28222
Caenorhabditis elegans	177902	WB:WBGene00007696
Xenopus laevis	398231	Xenbase:XB-GENE-960501
Danio rerio	406344	ZFIN:ZDB-GENE-040426-2024	DANRE19730
Canis lupus familiaris	474936		CANLF02850
Ciona intestinalis	494421		CIOIN05685
Bos taurus	617287		BOVIN18665
Macaca mulatta	708636		MACMU34621
Monodelphis domestica	100016717		MONDO14006