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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
Summary
- Gene Symbol
-
- Hadha
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Fatty acid metabolism
- Lyase
- Methylation
- Mitochondrion inner membrane
- Multifunctional enzyme
- NAD
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Transferase
- Transit peptide
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8BMS1 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cardiolipin acyl-chain remodeling | ||
| response to xenobiotic stimulus | ||
| response to insulin | ||
| fatty acid beta-oxidation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrial inner membrane | ||
| mitochondrion | ||
| mitochondrial fatty acid beta-oxidation multienzyme complex | ||
| mitochondrial nucleoid |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| long-chain-3-hydroxyacyl-CoA dehydrogenase activity | ||
| acetyl-CoA C-acyltransferase activity | ||
| NAD binding | ||
| enoyl-CoA hydratase activity |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- trifunctional enzyme subunit alpha, mitochondrial
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- I: Lipid transport and metabolism
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0111277 | mitochondrial trifunctional protein deficiency | |
| DOID:10652 | Alzheimer's disease | |
| DOID:3146 | lipid metabolism disorder | |
| DOID:9452 | steatotic liver disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 3030 | HGNC:4801 | HUMAN61814 | ||
| 34276 | FB:FBgn0028479 | |||
| 170670 | 10116_1:00244d | RGD:620512 | RATNO35571 | |
| 172310 | WB:WBGene00020347 | |||
| 180037 | WB:WBGene00001150 | |||
| 281810 | BOVIN02838 | |||
| 394832 | Xenbase:XB-GENE-959219 | |||
| 397012 | PIGXX22424 | |||
| 459079 | PANTR27210 | |||
| 553401 | ZFIN:ZDB-GENE-031222-5 | DANRE20354 |
