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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
Summary
- Gene Symbol
-
- Hadha
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Fatty acid metabolism
- Lyase
- Methylation
- Mitochondrion inner membrane
- Multifunctional enzyme
- NAD
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Transferase
- Transit peptide
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8BMS1 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cardiolipin acyl-chain remodeling | ||
| response to xenobiotic stimulus | ||
| response to insulin | ||
| fatty acid beta-oxidation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrial inner membrane | ||
| mitochondrion | ||
| mitochondrial fatty acid beta-oxidation multienzyme complex | ||
| mitochondrial nucleoid |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex binding | ||
| 3-hydroxyacyl-CoA dehydratase activity | ||
| fatty-acyl-CoA binding | ||
| 3-hydroxyacyl-CoA dehydrogenase activity | ||
| NAD+ binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- trifunctional enzyme subunit alpha, mitochondrial
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- I: Lipid transport and metabolism
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0111277 | mitochondrial trifunctional protein deficiency | |
| DOID:10652 | Alzheimer's disease | |
| DOID:3146 | lipid metabolism disorder | |
| DOID:9452 | steatotic liver disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 101724137 | 10181_0:00098a | HETGA10001 | ||
| 101815112 | FICAL14124 | |||
| 101836365 | 10036_0:003967 | |||
| 101871735 | MELUD08764 | |||
| 101942783 | CHRPI19598 | |||
| 101955476 | 43179_0:003883 | |||
| 101999538 | 79684_0:0030c0 | |||
| 102010469 | 34839_0:00331d | CHILA16759 | ||
| 102142372 | MACFA07856 | |||
| 102189046 | CAPHI02156 |
