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Rho GTPase activating protein 32

Summary

Gene Symbol

ARHGAP32

Organism

Homo sapiens (human)

External Links

NCBI Gene

9743

PubChem

9743

Alliance of Genome Resources

HGNC:17399

Annotation

Keyword

3D-structure
Alternative splicing
Cell projection
Cytoplasm
Endoplasmic reticulum
Endosome
GTPase activation
Golgi apparatus
Membrane
Methylation
Phosphoprotein
Reference proteome
SH3 domain
Synapse

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q86T64
A7KAX9	Brain-specific Rho GTPase-activating protein GAB-associated Cdc42/Rac GTPase-activating protein GC-GAP GTPase regulator interacting with TrkA Rho-type GTPase-activating protein 32 Rho/Cdc42/Rac GTPase-activating protein RICS RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling p200RhoGAP p250GAP

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
small GTPase mediated signal transduction	IBA
regulation of small GTPase mediated signal transduction	TAS

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

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GO Term	Evidence Code	PMID
Golgi membrane	IEA
fibrillar center	IDA
fibrillar center	IBA
nucleoplasm	IDA
nucleoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm [inference]

cell cortex

cytosol

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

postsynaptic specialization [inference]

postsynaptic density

postsynapse [inference]

dendritic spine

Displaying **all 4** entries
GO Term	Evidence Code	PMID
GTPase activator activity	TAS
GTPase activator activity	IBA
protein binding	IPI	12788081 15778465 25416956 29892012 31980649 32296183 35044719 36931259
phosphatidylinositol phosphate binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

rho gtpase-activating protein 32

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
phosphatidylinositol binding
small GTPase-mediated signal transduction

Displaying **all 5** entries
InterPro
PX domain superfamily
Rho GTPase activation protein
Rho GTPase-activating protein domain
SH3 domain
SH3-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 90 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	9743	Xenbase:XB-GENE-1002474
Caenorhabditis elegans	12549	WB:WBGene00009800
Caenorhabditis elegans	57514	WB:WBGene00009800
Drosophila melanogaster	115703	FB:FBgn0032821
Drosophila melanogaster	226652	FB:FBgn0032821
Drosophila melanogaster	257106	FB:FBgn0032821
Rattus norvegicus	315530		RATNO39962
Mus musculus	330914	Xenbase:XB-GENE-1002474	MOUSE60785
Pan troglodytes	451663		PANTR04725
Canis lupus familiaris	489283		CANLF15090