GlyCosmos Portal

Submissions

FERM and PDZ domain containing 4

Summary

Gene Symbol

FRMPD4

Organism

Homo sapiens (human)

External Links

NCBI Gene

9758

PubChem

9758

Alliance of Genome Resources

HGNC:29007

JoGo

FRMPD4

TogoVar

FRMPD4

Annotation

Keyword

3D-structure
Cell projection
Disease variant
Intellectual disability
Lipid-binding
Proteomics identification
Reference proteome
Synapse

Proteins

Displaying **all 5** entries
UniProt	Protein Name
A0A087WYX8	PDZ domain-containing protein 10 PSD-95-interacting regulator of spine morphogenesis
B7ZLE1	PDZ domain-containing protein 10 PSD-95-interacting regulator of spine morphogenesis
Q14CM0	PDZ domain-containing protein 10 PSD-95-interacting regulator of spine morphogenesis
A0A5F9ZH12	PDZ domain-containing protein 10 PSD-95-interacting regulator of spine morphogenesis
A0A6Q8PH73	PDZ domain-containing protein 10 PSD-95-interacting regulator of spine morphogenesis

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
positive regulation of synapse structural plasticity	IMP	19118189

GO Hierarchy

biological process

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of synapse structural plasticity

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of synapse structural plasticity

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse structural plasticity [inference]

positive regulation of synapse structural plasticity

positive regulation of cellular component organization [inference]

positive regulation of synapse structural plasticity

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoskeleton	IEA
protein-containing complex	IDA	22074847
dendritic spine	IDA	19118189
dendritic spine	IBA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

postsynapse [inference]

dendritic spine

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	19118189 22074847 24550280 29267967 30126976
phosphatidylinositol-4,5-bisphosphate binding	IDA	19118189
phosphatidylinositol-4,5-bisphosphate binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

FERM and PDZ domain-containing protein 4

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
phosphatidylinositol-4,5-bisphosphate binding

Displaying entries **1 - 10** of 11 in total

1

2

Next ›

Last »
InterPro
Band 4.1 domain
FAK1-like, FERM domain C-lobe
FERM and PDZ domain-containing protein 1/3/4, FERM domain C-lobe
FERM central domain
FERM domain
FERM superfamily, second domain
FERM/acyl-CoA-binding protein superfamily
PDZ domain
PDZ superfamily
PH-like domain superfamily