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adhesion G protein-coupled receptor E5

Summary

Gene Symbol

ADGRE5

Organism

Homo sapiens (human)

External Links

NCBI Gene

976

PubChem

976

Alliance of Genome Resources

HGNC:1711

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Cell adhesion
Cell membrane
Disulfide bond
EGF-like domain
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P48960	Leukocyte antigen CD97

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
inflammatory response	TAS	8955192
immune response	TAS	7636245
cell adhesion	IEA
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	TAS	8955192

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

cell communication [inference]

cell-cell signaling

cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IBA
focal adhesion	HDA	21423176
membrane	HDA	19946888
secretory granule membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane

bounding membrane of organelle [inference]

secretory granule membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	TAS	7636245
G protein-coupled receptor activity	IBA
calcium ion binding	IEA
protein binding	IPI	11297558 22210915 9064337

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

adhesion g protein-coupled receptor l2

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell surface receptor signaling pathway

Ortholog

Displaying entries **1 - 10** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	976	Xenbase:XB-GENE-952950
Xenopus tropicalis	2015	Xenbase:XB-GENE-950605
Xenopus tropicalis	5641	Xenbase:XB-GENE-950605
Xenopus tropicalis	13733	Xenbase:XB-GENE-950605
Xenopus tropicalis	19141	Xenbase:XB-GENE-950605
Drosophila melanogaster	22859	FB:FBgn0033313
Drosophila melanogaster	23266	FB:FBgn0033313
Drosophila melanogaster	23284	FB:FBgn0033313
Mus musculus	26364	Xenbase:XB-GENE-952950	MOUSE57996
Xenopus tropicalis	30817	Xenbase:XB-GENE-950605