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G3BP stress granule assembly factor 2

Summary

Gene Symbol

G3BP2

Organism

Homo sapiens (human)

External Links

NCBI Gene

9908

PubChem

9908

Alliance of Genome Resources

HGNC:30291

JoGo

G3BP2

TogoVar

G3BP2

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Direct protein sequencing
Host-virus interaction
Innate immunity
Isopeptide bond
Methylation
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Ubl conjugation
mRNA transport

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A7I2V647
A0A7I2V3P9
Q9UN86	GAP SH3 domain-binding protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cytoplasmic sequestering of NF-kappaB
Ras protein signal transduction	NAS	9575347
stress granule assembly	IDA	27022092 32302570 32302571 32302572
stress granule assembly	IBA
innate immune response	IEA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

stress granule assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

stress granule assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

establishment of RNA localization [inference]

RNA transport [inference]

mRNA transport

maintenance of location [inference]

maintenance of protein location [inference]

cytoplasmic sequestering of protein [inference]

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

regulation of organelle assembly [inference]

regulation of stress granule assembly [inference]

positive regulation of stress granule assembly

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

regulation of organelle assembly [inference]

regulation of stress granule assembly [inference]

positive regulation of stress granule assembly

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of stress granule assembly

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity [inference]

cytoplasmic sequestering of NF-kappaB

cytoplasmic sequestering of transcription factor [inference]

cytoplasmic sequestering of NF-kappaB

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cytoplasm	NAS	10969074
cytosol	TAS
cytosol	IDA
cytosol	IBA
cytoplasmic stress granule	IMP	23279204

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
RNA binding	HDA	22658674 22681889
mRNA binding	IBA
protein binding	IPI	19615732 23279204 25416956 25893917 28514442 29892012 31515488 32296183 32353859 32838362 33060197 33495715 33845483 33961781 34029587 34232536 34400613 34578187 34780058 34799561 34901782 35271311 36217029 36217030
signaling receptor complex adaptor activity	NAS	10969074
molecular condensate scaffold activity	IDA	32302570 32302571 32302572