GlyCosmos Portal

Annotation

Keyword

Acyltransferase
Endoplasmic reticulum
Phospholipid biosynthesis
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q92604	2-acylglycerophosphocholine O-acyltransferase Acyl-CoA:monoacylglycerol acyltransferase LPGAT1 Lysophospholipid acyltransferase 7 Stearoyl-CoA:1-lyso-2-acyl-PE acyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
triglyceride biosynthetic process	ISS
positive regulation of fatty acid biosynthetic process	IMP	23749231
phospholipid biosynthetic process	IEA
phosphatidylethanolamine acyl-chain remodeling	ISS
phosphatidylglycerol acyl-chain remodeling

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

phospholipid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

phospholipid biosynthetic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

phospholipid biosynthetic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

phospholipid biosynthetic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

phospholipid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

phospholipid biosynthetic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylethanolamine acyl-chain remodeling

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidylinositol metabolic process [inference]

phosphatidylinositol acyl-chain remodeling

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of cellular biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of cellular biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of small molecule metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of cellular biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IBA
cytoplasm	IDA	10942595
endoplasmic reticulum membrane	IMP TAS	15485873
endomembrane system	IBA
membrane	HDA	19946888

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
2-acylglycerophosphocholine O-acyltransferase activity	IDA	36049524
1-acylglycerol-3-phosphate O-acyltransferase activity
2-acylglycerol O-acyltransferase activity	ISS
acyltransferase activity	IBA
2-acylglycerol-3-phosphate O-acyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity [inference]

acylglycerol O-acyltransferase activity [inference]

lysophospholipid acyltransferase activity

lysophosphatidic acid acyltransferase activity [inference]

lysophosphatidylethanolamine acyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K13514

Name

lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]

References

15485873

Rhea

RHEA:10332

a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA

CoA + a 1,2-diacyl-sn-glycero-3-phosphocholine

Enzyme

2.3.1.62

PMID

RHEA:16741

a 2-acylglycerol + an acyl-CoA

a 1,2-diacylglycerol + CoA

Enzyme

2.3.1.22

PMID

12621063

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:1470	major depressive disorder	DisGeNET
DOID:1595	melancholic depression	DisGeNET DisGeNET
DOID:1596	depressive disorder	DisGeNET
DOID:2848	obsolete melancholia	DisGeNET DisGeNET
DOID:4964	neurotic disorder	DisGeNET
DOID:9970	obesity	DisGeNET

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP001230
Gene Name: lysophosphatidylglycerol acyltransferase 1

Ortholog

Displaying entries **21 - 30** of 80 in total

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Species	Gene ID	Orthologous MAtrix
Macaca fascicularis	102115662	MACFA20405
Macaca mulatta	711398	MACMU22257
Macaca nemestrina	105493565	MACNE05931
Papio anubis	101021800	PAPAN18052
Mandrillus leucophaeus	105536396	MANLE10317
Gorilla gorilla gorilla	101132115	GORGO21220
Pan paniscus	100976771	PANPA03720
Pan troglodytes	745964	PANTR23630
Pongo abelii	100450766	PONAB16909
Canis lupus familiaris	609933	CANLF17119

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements