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cell division cycle 25A

Summary

Gene Symbol

CDC25A

Organism

Homo sapiens (human)

External Links

NCBI Gene

993

PubChem

993

Alliance of Genome Resources

HGNC:1725

JoGo

CDC25A

TogoVar

CDC25A

Annotation

Keyword

3D-structure
Alternative splicing
Mitosis
Phosphoprotein
Protein phosphatase
Proteomics identification
Reference proteome
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
K7N7S0
P30304	Dual specificity phosphatase Cdc25A
D8KXX0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 14 in total

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GO Term	Evidence Code	PMID
chromatin remodeling	IEA
cell population proliferation	TAS	11139144
response to radiation	IDA	21376736
positive regulation of G2/M transition of mitotic cell cycle	IDA	20360007
positive regulation of G2/M transition of mitotic cell cycle	IBA

GO Hierarchy

biological process

cellular process [inference]

cell population proliferation

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

cell cycle G2/M phase transition [inference]

G2/M transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

mitotic cell cycle process [inference]

mitotic cell cycle phase transition [inference]

cell division

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation

response to light stimulus [inference]

response to UV [inference]

cellular response to UV

cellular response to light stimulus [inference]

cellular response to UV

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA replication

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle process [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of meiotic cell cycle phase transition [inference]

regulation of G2/MI transition of meiotic cell cycle [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of G2/MI transition of meiotic cell cycle [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of meiotic cell cycle phase transition [inference]

regulation of G2/MI transition of meiotic cell cycle [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of transferase activity [inference]

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

regulation of cyclin-dependent protein kinase activity [inference]

regulation of cyclin-dependent protein serine/threonine kinase activity

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IBA
nucleoplasm	TAS
cytoplasm	IBA
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
phosphoprotein phosphatase activity	TAS
phosphoprotein phosphatase activity	IDA	20360007
protein tyrosine phosphatase activity	IDA	20360007
protein tyrosine phosphatase activity	IBA
non-membrane spanning protein tyrosine phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein-folding chaperone binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:11054	urinary bladder cancer	Alliance of Genome Resources
DOID:4362	cervical cancer	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

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Acknowledgements