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MIRAGE
heparan sulfate-glucosamine 3-sulfotransferase 2

Summary
Gene Symbol
  • HS3ST2
Aliases
  • 3OST2
Organism
Homo sapiens (human)
NCBI Gene
9956
GGDB ID
HGNC
5195
mRNA
map
  • 16p12
Protein
OMIM
KEGG Gene ID
hsa:9956
PubChem
9956
Alliance of Genome Resources
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Transferase
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q9Y278
  • Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
glycosaminoglycan biosynthetic process
heparan sulfate proteoglycan biosynthetic process, enzymatic modification
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Heparan sulfate glucosamine 3-O-sulfotransferase
Functional Category
  • G: Carbohydrate transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
Displaying all 3 entries
Gene Ontology
[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity
sulfotransferase activity
transferase activity
Displaying all 3 entries
InterPro
Heparan sulfate sulfotransferase
P-loop containing nucleoside triphosphate hydrolase
Sulfotransferase domain
GlycoGene Database (GGDB)
GGDB ID
gg015
Gene Symbol
  • HS3ST2
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Mus musculus XP_112440 XM_112440
Rattus norvegicus NP_852035 NM_181370
KEGG BRITE Database
Orthology
K07808
Name
[heparan sulfate]-glucosamine 3-sulfotransferase 2 [EC:2.8.2.29]
References
Rhea

RHEA:15461

3'-phosphoadenylyl sulfate
H+ + adenosine 3',5'-bisphosphate
Enzyme
PMID
Disease
Disease Ontology
Displaying all 4 entries
DO ID Disease Name Source
DOID:1324 lung cancer
DOID:1793 pancreatic cancer
DOID:219 colon cancer
DOID:3908 lung non-small cell carcinoma
Ortholog
Displaying entries 71 - 80 of 91 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
107574133 SINGR100982
108256804 ICTPU19018
108701605 Xenbase:XB-GENE-980910
108703165 Xenbase:XB-GENE-980910
109053513 CYPCA22529
109087956 CYPCA01825
112908295 VULVU34054
113575522 ELEEL03943
113883708 BOBOX17671
114025899 VOMUR02156
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025