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2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase

Summary

Gene Symbol

arfB

Organism

Methanothermus fervidus DSM 2088

External Links

NCBI Gene: 9962966
PubChem: 9962966

Annotation

Keyword

Hydrolase
Iron
Metal-binding
Reference proteome
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
E3GWT5	Formamide hydrolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
riboflavin biosynthetic process
F420-0 metabolic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

flavin-containing compound metabolic process [inference]

riboflavin metabolic process [inference]

riboflavin biosynthetic process

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

organonitrogen compound metabolic process [inference]

flavin-containing compound metabolic process [inference]

riboflavin metabolic process [inference]

riboflavin biosynthetic process

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

F420-0 metabolic process

organonitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

riboflavin biosynthetic process

heterocycle biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

riboflavin biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

organonitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

F420-0 metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

alditol phosphate metabolic process [inference]

pentitol phosphate metabolic process [inference]

ribitol phosphate metabolic process [inference]

F420-0 metabolic process

organophosphate metabolic process [inference]

alditol phosphate metabolic process [inference]

pentitol phosphate metabolic process [inference]

ribitol phosphate metabolic process [inference]

F420-0 metabolic process

cellular nitrogen compound metabolic process [inference]

flavin-containing compound metabolic process [inference]

riboflavin metabolic process [inference]

riboflavin biosynthetic process

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

riboflavin biosynthetic process

heterocycle biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

flavin-containing compound metabolic process [inference]

riboflavin metabolic process [inference]

riboflavin biosynthetic process

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

F420-0 metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

aldonic acid metabolic process [inference]

F420-0 metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

F420-0 metabolic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

riboflavin metabolic process [inference]

riboflavin biosynthetic process

water-soluble vitamin biosynthetic process [inference]

riboflavin biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

riboflavin biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

riboflavin biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

aldonic acid metabolic process [inference]

F420-0 metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

F420-0 metabolic process

organophosphate metabolic process [inference]

alditol phosphate metabolic process [inference]

pentitol phosphate metabolic process [inference]

ribitol phosphate metabolic process [inference]

F420-0 metabolic process

carbohydrate derivative metabolic process [inference]

alditol phosphate metabolic process [inference]

pentitol phosphate metabolic process [inference]

ribitol phosphate metabolic process [inference]

F420-0 metabolic process

organic cyclic compound metabolic process [inference]

flavin-containing compound metabolic process [inference]

riboflavin metabolic process [inference]

riboflavin biosynthetic process

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

F420-0 metabolic process

organic cyclic compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

organonitrogen compound metabolic process [inference]

flavin-containing compound metabolic process [inference]

riboflavin metabolic process [inference]

riboflavin biosynthetic process

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

F420-0 metabolic process

organonitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

organonitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

F420-0 metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

alditol phosphate metabolic process [inference]

pentitol phosphate metabolic process [inference]

ribitol phosphate metabolic process [inference]

F420-0 metabolic process

organophosphate metabolic process [inference]

alditol phosphate metabolic process [inference]

pentitol phosphate metabolic process [inference]

ribitol phosphate metabolic process [inference]

F420-0 metabolic process

cellular nitrogen compound metabolic process [inference]

flavin-containing compound metabolic process [inference]

riboflavin metabolic process [inference]

riboflavin biosynthetic process

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

riboflavin biosynthetic process

heterocycle biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

flavin-containing compound metabolic process [inference]

riboflavin metabolic process [inference]

riboflavin biosynthetic process

flavin-containing compound biosynthetic process [inference]

riboflavin biosynthetic process

F420-0 metabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
ferrous iron binding
2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [inference]

2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding [inference]

ferrous iron binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:27282

H₂O + 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

H⁺ + formate + 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate

Enzyme

3.5.1.102

PMID

19309161

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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