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adhesion G protein-coupled receptor L2

Summary

Gene Symbol

Adgrl2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

99633

PubChem

99633

Alliance of Genome Resources

MGI:2139714

Annotation

Keyword

Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A0G2JGM8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
response to bacterium	IEP	23012479
cell surface receptor signaling pathway	IEA
synapse organization	IDA IMP	28972101
G protein-coupled receptor signaling pathway	IEA
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane
postsynaptic membrane	IDA IMP	28972101
plasma membrane	IBA
glutamatergic synapse	IDA IMP	28972101

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

Displaying **all 3** entries
GO Term	Evidence Code	PMID
PDZ domain binding	ISO
G protein-coupled receptor activity	IBA IEA
carbohydrate binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

protein domain specific binding [inference]

PDZ domain binding

carbohydrate binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

adhesion G protein-coupled receptor L2

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism

Displaying 1 entry
Gene Ontology
cell surface receptor signaling pathway

Displaying entries **1 - 10** of 13 in total

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InterPro
D-galactoside/L-rhamnose binding SUEL lectin domain superfamily
D-galactoside/L-rhamnose binding SUEL lectin domain
GAIN domain superfamily
GAIN domain, N-terminal
GPCR family 2, extracellular hormone receptor domain superfamily
GPCR, family 2, extracellular hormone receptor domain
GPCR, family 2, latrophilin, C-terminal
GPCR, family 2, latrophilin
GPCR, family 2, secretin-like, conserved site
GPCR, family 2, secretin-like

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1094	attention deficit hyperactivity disorder	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **126** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	23266		HGNC:18582	HUMAN50525
Drosophila melanogaster	35846		FB:FBgn0033313
Danio rerio	57987		ZFIN:ZDB-GENE-000607-49	DANRE01879
Rattus norvegicus	171447	10116_1:000fcd	RGD:620835	RATNO23013
Caenorhabditis elegans	173771		WB:WBGene00002252
Caenorhabditis elegans	174419		WB:WBGene00002251
Pan troglodytes	456974			PANTR21458
Canis lupus familiaris	490193			CANLF16967
Macaca mulatta	708998			MACMU22999
Monodelphis domestica	100013683			MONDO11546