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mediator complex subunit 12

Summary

Gene Symbol

MED12

Organism

Homo sapiens (human)

External Links

NCBI Gene

9968

PubChem

9968

Alliance of Genome Resources

HGNC:11957

Annotation

Keyword

Acetylation
Activator
Alternative splicing
Direct protein sequencing
Disease variant
Intellectual disability
Methylation
Nucleus
Phosphoprotein
Reference proteome
Repressor
Transcription regulation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q93074	Activator-recruited cofactor 240 kDa component CAG repeat protein 45 Mediator complex subunit 12 OPA-containing protein Thyroid hormone receptor-associated protein complex 230 kDa component Trinucleotide repeat-containing gene 11 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
neural tube closure	IEA
endoderm development	IEA
heart development	IEA
oligodendrocyte development	IEA
Schwann cell development	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

non-canonical Wnt signaling pathway [inference]

Wnt signaling pathway, planar cell polarity pathway

cellular developmental process [inference]

cell development [inference]

glial cell development [inference]

multicellular organismal process [inference]

stem cell population maintenance [inference]

somatic stem cell population maintenance

developmental process [inference]

anatomical structure morphogenesis [inference]

post-anal tail morphogenesis

embryonic morphogenesis [inference]

embryonic neurocranium morphogenesis

anatomical structure formation involved in morphogenesis [inference]

tube formation [inference]

tube closure [inference]

neural tube closure

anatomical structure development [inference]

tissue development [inference]

endoderm development

spinal cord development

cell development [inference]

glial cell development [inference]

animal organ development [inference]

heart development

embryonic organ development [inference]

embryonic brain development

cellular developmental process [inference]

cell development [inference]

glial cell development [inference]

maintenance of cell number [inference]

stem cell population maintenance [inference]

somatic stem cell population maintenance

growth [inference]

developmental growth [inference]

developmental growth involved in morphogenesis [inference]

axis elongation [inference]

axis elongation involved in somitogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

non-canonical Wnt signaling pathway [inference]

Wnt signaling pathway, planar cell polarity pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

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GO Term	Evidence Code	PMID
ubiquitin ligase complex	IEA
nucleus	IDA	10235267 17000779
nucleoplasm	TAS
membrane	HDA	19946888
mediator complex	IDA	10198638 12037571

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

mediator complex

nuclear cyclin-dependent protein kinase holoenzyme complex [inference]

CKM complex

intracellular protein-containing complex [inference]

ubiquitin ligase complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex

transferase complex, transferring phosphorus-containing groups [inference]

protein kinase complex [inference]

serine/threonine protein kinase complex [inference]

cyclin-dependent protein kinase holoenzyme complex [inference]

nuclear cyclin-dependent protein kinase holoenzyme complex [inference]

CKM complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

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GO Term	Evidence Code	PMID
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
chromatin binding	IEA
transcription coregulator activity	IDA	10198638
transcription coactivator activity	NAS	10235266
transcription coactivator activity	IDA	12037571 12218053

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

binding [inference]

protein binding

beta-catenin binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

nuclear receptor binding [inference]

protein-containing complex binding [inference]

chromatin binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

transcription regulator activity [inference]

transcription coregulator activity

transcription coactivator activity

nuclear receptor coactivator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Mediator of RNA polymerase II transcription subunit 12

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Mediator complex, subunit Med12, LCEWAV-domain
Mediator complex, subunit Med12

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0080985	syndromic X-linked intellectual disorder Lujan-Fryns-type	Alliance of Genome Resources
DOID:1470	major depressive disorder	Alliance of Genome Resources
DOID:14711	FG syndrome	Alliance of Genome Resources
DOID:1967	leiomyosarcoma	Alliance of Genome Resources
DOID:591	phobic disorder	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	9968	Xenbase:XB-GENE-985871
Mus musculus	59024		MOUSE66647
Pan troglodytes	449626		PANTR46236
Bos taurus	520974		BOVIN36915
Danio rerio	566632		DANRE07485
Rattus norvegicus	679693		RATNO45381
Macaca mulatta	696791		MACMU48327
Xenopus tropicalis	850442	Xenbase:XB-GENE-985871
Equus caballus	100056909		HORSE43478
Pongo abelii	100127097		PONAB37545

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements