RES
1r:r1
REP
REP1:2o(8+2)2d=-1--1
RES
2b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
3s:n-acetyl
LIN
1:2d(5+1)3n

• Bos MP et al. Viability of a capsule- and lipopolysaccharide-deficient mutant of Neisseria meningitidis. Infect Immun. 2005 Sep;73:(9):6194-7. doi: 10.1128/IAI.73.9.6194-6197.2005. PMID: 16113348.

• Ortiz AI et al. In vitro synthesis of colominic acid by membrane-bound sialyltransferase of Escherichia coli K-235. Kinetic properties of this enzyme and inhibition by CMP and other cytidine nucleotides. Eur J Biochem. 1989 Jan 2;178:(3):741-9. doi: 10.1111/j.1432-1033.1989.tb14505.x. PMID: 2643517.

• Henderson TJ et al. Conformational flexibility of the group B meningococcal polysaccharide in solution. J Am Chem Soc. 2003 Mar 12;125:(10):2930-9. doi: 10.1021/ja0210087. PMID: 12617660.

• Ferrero MA et al. N-acetyl-D-neuraminic acid lyase generates the sialic acid for colominic acid biosynthesis in Escherichia coli K1. Biochem J. 1996 Jul 1;317 ( Pt 1):157-65. doi: 10.1042/bj3170157. PMID: 8694758.

• Patane J et al. Preparative production of colominic acid oligomers via a facile microwave hydrolysis. Carbohydr Res. 2009 Apr 21;344:(6):820-4. doi: 10.1016/j.carres.2009.01.013. PMID: 19281967.

• Steeghs L et al. Outer membrane composition of a lipopolysaccharide-deficient Neisseria meningitidis mutant. EMBO J. 2001 Dec 17;20:(24):6937-45. doi: 10.1093/emboj/20.24.6937. PMID: 11742971.

• Azmi FH et al. Variable region sequences and idiotypic expression of a protective human immunoglobulin M antibody to capsular polysaccharides of Neisseria meningitidis group B and Escherichia coli K1. Infect Immun. 1994 May;62:(5):1776-86. doi: 10.1128/IAI.62.5.1776-1786.1994. PMID: 8168940.

• Ovodov YS et al. Bacterial capsular antigens. Structural patterns of capsular antigens. Biochemistry (Mosc). 2006 Sep;71:(9):937-54. doi: 10.1134/s000629790609001x. PMID: 17009947.

• Flaherty TM et al. 2D NMR analysis of the polylactone derivative of colominic acid. Complete 1H and 13C NMR chemical shift assignments. Carbohydr Res. 1996 Feb 7;281:(1):173-7. doi: 10.1016/0008-6215(95)00330-4. PMID: 8839184.

• Tzeng YL et al. Translocation and surface expression of lipidated serogroup B capsular Polysaccharide in Neisseria meningitidis. Infect Immun. 2005 Mar;73:(3):1491-505. doi: 10.1128/IAI.73.3.1491-1505.2005. PMID: 15731047.

• Jiménez N et al. Effects of lipopolysaccharide biosynthesis mutations on K1 polysaccharide association with the Escherichia coli cell surface. J Bacteriol. 2012 Jul;194:(13):3356-67. doi: 10.1128/JB.00329-12. PMID: 22522903.

• Barrallo S et al. Regulation of capsular polysialic acid biosynthesis by temperature in Pasteurella haemolytica A2. FEBS Lett. 1999 Feb 26;445:(2-3):325-8. doi: 10.1016/s0014-5793(99)00163-5. PMID: 10094482.

• Kabat EA et al. The epitope associated with the binding of the capsular polysaccharide of the group B meningococcus and of Escherichia coli K1 to a human monoclonal macroglobulin, IgMNOV. J Exp Med. 1988 Aug 1;168:(2):699-711. doi: 10.1084/jem.168.2.699. PMID: 2457648.

• Moe GR et al. Epitopes recognized by a nonautoreactive murine anti-N-propionyl meningococcal group B polysaccharide monoclonal antibody. Infect Immun. 2005 Apr;73:(4):2123-8. doi: 10.1128/IAI.73.4.2123-2128.2005. PMID: 15784554.

• Whitfield C et al. Biosynthesis and expression of cell-surface polysaccharides in gram-negative bacteria. Adv Microb Physiol. 1993;35:135-246. doi: 10.1016/s0065-2911(08)60099-5. PMID: 8310880.

• Steenbergen SM et al. Functional relationships of the sialyltransferases involved in expression of the polysialic acid capsules of Escherichia coli K1 and K92 and Neisseria meningitidis groups B or C. J Biol Chem. 2003 Apr 25;278:(17):15349-59. doi: 10.1074/jbc.M208837200. PMID: 12578835.

• Yongye AB et al. The conformational properties of methyl alpha-(2,8)-di/trisialosides and their N-acyl analogues: implications for anti-Neisseria meningitidis B vaccine design. Biochemistry. 2008 Nov 25;47:(47):12493-514. doi: 10.1021/bi800431c. PMID: 18954144.

• Swartley JS et al. Membrane glycerophospholipid biosynthesis in Neisseria meningitidis and Neisseria gonorrhoeae: identification, characterization, and mutagenesis of a lysophosphatidic acid acyltransferase. Mol Microbiol. 1995 Nov;18:(3):401-12. doi: 10.1111/j.1365-2958.1995.mmi_18030401.x. PMID: 8748025.

• Moe GR et al. Molecular analysis of anti-N-propionyl Neisseria meningitidis group B polysaccharide monoclonal antibodies. Mol Immunol. 2006 Mar;43:(9):1424-31. doi: 10.1016/j.molimm.2005.07.033. PMID: 16140379.

• Mandrell RE et al. Complement-mediated bactericidal activity of human antibodies to poly alpha 2-->8 N-acetylneuraminic acid, the capsular polysaccharide of Neisseria meningitidis serogroup B. J Infect Dis. 1995 Nov;172:(5):1279-89. doi: 10.1093/infdis/172.5.1279. PMID: 7594665.

• Vann WF et al. The NeuC protein of Escherichia coli K1 is a UDP N-acetylglucosamine 2-epimerase. J Bacteriol. 2004 Feb;186:(3):706-12. doi: 10.1128/jb.186.3.706-712.2004. PMID: 14729696.

• Ferrero MA et al. Biosynthesis and production of polysialic acids in bacteria. Appl Microbiol Biotechnol. 2010 May;86:(6):1621-35. doi: 10.1007/s00253-010-2531-5. PMID: 20349183.