G31736BK

Summary
GlyTouCan ID
G31736BK
IUPAC Condensed
GalNAc(b1-4)GlcNAc(?1-
Motifs
LDN LacdiNAc
Subsumption Level
Linkage-defined saccharide
Monoisotopic Mass
424.17
GlyGen
ChEBI
PubChem Compound
PubChem Substance
CarbBank
39475 45010
3D Structures
GlycoShape
Organisms
KEGG BRITE Database
KEGG ID
References
GlycoEpitope
Epitope ID
EP0150
Sequence Descriptors
GlycoCT
RES
1b:x-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(4+1)3d
3:3d(2+1)4n
WURCS
WURCS=2.0/2,2,1/[a2122h-1x_1-5_2*NCC/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2/a4-b1
Literature
Displaying entries 31 - 40 of 62 in total
PubMed ID Title First Author Publication Date Source
22474328 O-Linked N,N′-Diacetyllactosamine (LacdiNAc)-modified Glycans in Extracellular Matrix Glycoproteins Are Specifically Phosphorylated at Subterminal N-Acetylglucosamine Breloy I 2012 May 25
  • PubChem
22298779 Bivalent Carbohydrate Binding Is Required for Biological Activity of Clitocybe nebularis Lectin (CNL), the N,N′-Diacetyllactosediamine (GalNAcβ1–4GlcNAc, LacdiNAc)-specific Lectin from Basidiomycete C. nebularis Pohleven J 2012 Mar 23
  • PubChem
22653491 Priming mass spectrometry-based sulfoglycomic mapping for identification of terminal sulfated lacdiNAc glycotope Yu SY 2012 Jun 01
  • PubChem
22241826 Structural characterization of Schistosoma mansoni adult worm glycosphingolipids reveals pronounced differences with those of cercariae Frank S 2012 Jan 11
  • PubChem
21372247 Targeted Glycoproteomic Analysis Reveals That Kappa-5 is a Major, Uniquely Glycosylated Component of Schistosoma mansoni Egg Antigens Meevissen MHJ 2011 May
  • PubChem
21305673 LacdiNAc (GalNAcβ1-4GlcNAc) Contributes to Self-Renewal of Mouse Embryonic Stem Cells by Regulating Leukemia Inhibitory Factor/STAT3 Signaling Sasaki N 2011 Apr 01
  • PubChem
21030537 N-Glycosylation of total cellular glycoproteins from the human ovarian carcinoma SKOV3 cell line and of recombinantly expressed human erythropoietin Machado E 2010 Oct 28
  • PubChem
19179461 Synthesis of LacdiNAc-terminated glycoconjugates by mutant galactosyltransferase - A way to new glycodrugs and materials Bojarová P 2009 Jan 29
  • PubChem
19139268 Golgi targeting of Drosophila melanogaster β4GalNAcTB requires a DHHC protein family–related protein as a pilot Johswich A 2009 Jan 12
  • PubChem
18193481 Serum antibody screening by surface plasmon resonance using a natural glycan microarray de Boer AR 2008 Jan 12
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death.
  • Guillot-Sestier MV
  • Sunyach C
  • Ferreira ST
  • Marzolo MP
  • Bauer C
  • Thevenet A
  • Checler F
J Biol Chem 2012 Feb 10 22184125
Apical Golgi localization of N,N'-diacetyllactosediamine synthase, beta4GalNAc-T3, is responsible for LacdiNAc expression on gastric mucosa.
  • Ikehara Y
  • Sato T
  • Niwa T
  • Nakamura S
  • Gotoh M
  • Ikehara SK
  • Kiyohara K
  • Aoki C
  • Iwai T
  • Nakanishi H
  • Hirabayashi J
  • Tatematsu M
  • Narimatsu H
Glycobiology 2006 Sep 16728562
Gender-specific expression of complex-type N-glycans in schistosomes.
  • Wuhrer M
  • Koeleman CA
  • Fitzpatrick JM
  • Hoffmann KF
  • Deelder AM
  • Hokke CH
Glycobiology 2006 Oct 16825488
LacdiNAc- and LacNAc-containing glycans induce granulomas in an in vivo model for schistosome egg-induced hepatic granuloma formation.
  • Van de Vijver KK
  • Deelder AM
  • Jacobs W
  • Van Marck EA
  • Hokke CH
Glycobiology 2006 Mar 16282603
Novel poly-GalNAcbeta1-4GlcNAc (LacdiNAc) and fucosylated poly-LacdiNAc N-glycans from mammalian cells expressing beta1,4-N-acetylgalactosaminyltransferase and alpha1,3-fucosyltransferase.
  • Kawar ZS
  • Haslam SM
  • Morris HR
  • Dell A
  • Cummings RD
J Biol Chem 2005 Apr 1 15653684

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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