G55205ZV

Summary
GlyTouCan ID
G55205ZV
IUPAC Condensed
Gal(a1-4)Gal(b1-4)GlcNAc(?1-
Subsumption Level
Linkage-defined saccharide
Monoisotopic Mass
545.2
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GlycoShape
KEGG BRITE Database
KEGG ID
GlycoEpitope
Epitope ID
EP0046
Sequence Descriptors
GlycoCT
RES
1b:x-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-dgal-HEX-1:5
LIN
1:1d(2+1)2n
2:1o(4+1)3d
3:3o(4+1)4d
WURCS
WURCS=2.0/3,3,2/[a2122h-1x_1-5_2*NCC/3=O][a2112h-1b_1-5][a2112h-1a_1-5]/1-2-3/a4-b1_b4-c1
Literature
Displaying all 5 entries
PubMed ID Title First Author Publication Date Source
17991151 Normal human serum contains high levels of anti-Gal alpha 1-4GlcNAc antibodies Obukhova P 2007 Nov
  • PubChem
17006649 Presence of natural anti-Galalpha1-4GalNAcbeta1-3Gal (anti-NOR) antibodies in animal sera Duk M 2006 Nov
  • PubChem
16563047 H-deficient Bombay and para-Bombay red blood cells are most strongly agglutinated by the galactophilic lectins of Aplysia and Pseudomonas aeruginosa that detect I and P1 antigens Gilboa-Garber N 2006
  • GlyGen
  • GlycoEpitope
2456994 Monoclonal antibodies produced by immunization with neoglycoproteins containing Gal alpha 1-4Gal beta 1-4Glc beta-O and Gal alpha 1-4Gal beta 1-4GlcNAc beta-O residues: useful immunochemical and cytochemical reagents for blood group P antigens and a differentiation marker in Burkitt lymphoma and other B-cell malignancies Brodin NT 1988 Aug 15
  • PubChem
1182122 An immunochemical study of the human blood group P1, P, and PK glycosphingolipid antigens Naiki M 1975 Nov 04
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
Human Gb3/CD77 synthase produces P1 glycotope-capped N-glycans, which mediate Shiga toxin 1 but not Shiga toxin 2 cell entry.
  • Szymczak-Kulus K
  • Weidler S
  • Bereznicka A
  • Mikolajczyk K
  • Kaczmarek R
  • Bednarz B
  • Zhang T
  • Urbaniak A
  • Olczak M
  • Park EY
  • Majorczyk E
  • Kapczynska K
  • Lukasiewicz J
  • Wuhrer M
  • Unverzagt C
  • Czerwinski M
J Biol Chem 2021 Jan-Jun 33460651
Blood group P1 antigen-bearing glycoproteins are functional but less efficient receptors of Shiga toxin than conventional glycolipid-based receptors.
  • Morimoto K
  • Suzuki N
  • Tanida I
  • Kakuta S
  • Furuta Y
  • Uchiyama Y
  • Hanada K
  • Suzuki Y
  • Yamaji T
J Biol Chem 2020 Jul 10 32409578
The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle.
  • Iwamura K
  • Furukawa K
  • Uchikawa M
  • Sojka BN
  • Kojima Y
  • Wiels J
  • Shiku H
  • Urano T
  • Furukawa K
J Biol Chem 2003 Nov 7 12888565
Establishment of a monoclonal antibody directed against Gb3Cer/CD77: a useful immunochemical reagent for a differentiation marker in Burkitt's lymphoma and germinal centre B cells.
  • Miyamoto D
  • Ueno T
  • Takashima S
  • Ohta K
  • Miyawaki T
  • Suzuki T
  • Suzuki Y
Glycoconj J 1997 Apr 9147061
Gal alpha 4Gal-binding antibodies: specificity and use for the mapping of glycolipids of Burkitt lymphoma and other human tumors.
  • Lanne B
  • Jondal M
  • Karlsson KA
Glycobiology 1996 Jun 8842706

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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