G90387AM

Summary
GlyTouCan ID
G90387AM
IUPAC Condensed
Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(?1-
Motifs
3-Sialyl-LN (type 2) Lewis x Lex SSEA-1
Subsumption Level
Linkage-defined saccharide
Monoisotopic Mass
820.3
GlyGen
ChEBI
PubChem Compound
PubChem Substance
CarbBank
46377 46708
3D Structures
GlycoShape
KEGG BRITE Database
KEGG ID
References
Pathway
Displaying entries 1 - 10 of 12 in total
Pathway Name Organism
Lewis blood group biosynthesis Rattus norvegicus
Lewis blood group biosynthesis Sus scrofa
Lewis blood group biosynthesis Canis familiaris
Lewis blood group biosynthesis Drosophila melanogaster
Lewis blood group biosynthesis Bos taurus
Lewis blood group biosynthesis Mus musculus
Lewis blood group biosynthesis Caenorhabditis elegans
Lewis blood group biosynthesis Homo sapiens
Lewis blood group biosynthesis Xenopus tropicalis
Lewis blood group biosynthesis Gallus gallus
Sequence Descriptors
GlycoCT
RES
1b:x-dglc-HEX-1:5
2s:n-acetyl
3b:a-lgal-HEX-1:5|6:d
4b:b-dgal-HEX-1:5
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(4+1)4d
4:4o(3+2)5d
5:5d(5+1)6n
WURCS
WURCS=2.0/4,4,3/[a2122h-1x_1-5_2*NCC/3=O][a1221m-1a_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-4/a3-b1_a4-c1_c3-d2
Literature
Displaying entries 21 - 30 of 1046 in total
PubMed ID Title First Author Publication Date Source
37357420 Toward α‐1,3/4 fucosyltransferases targeted drug discovery: In silico uncovering of promising natural inhibitors of fucosyltransferase 6 Magdaleno JSL 2023 Jun 25
  • PubChem
37343170 Monoclonal Antibody F2 Reactive with Sialyl Lewis x Monoclonal Antibody F2 Reactive with Sialyl Lewis x 2023 Jun 01
  • PubChem
37057964 Therapeutic Effects of an Anti-Sialyl Lewis x Antibody in a Murine Model of Acute Lung Injury Liu W 2023 Jun 01
  • PubChem
37486674 Identification of potential classes of glycoligands mediating dynamic endothelial adhesion of human tumor cells Starzonek S 2023 Jul 24
  • PubChem
37486087 How E-, L-, and P-Selectins Bind to sLex and PSGL-1: A Quantification of Critical Residue Interactions Sladek V 2023 Jul 24
  • PubChem
37449872 Synthesis of Sialyl LewisX Mimetics with E- and P-Selectin Binding Properties and Immunosuppressive Activity Simard RD 2023 Jul 14
  • PubChem
37182470 Revisiting the structural basis for biological activity of GMI-1070, a sialyl Lewisx mimetic Arend LB 2023 Jul
  • PubChem
36648484 Sialyl Lewis X mediates interleukin-1 beta-induced trophoblast adhesion to endometrial cells during human embryo implantation Ma Z 2023 Jan 16
  • PubChem
37074623 ST3GalIV drives SLeX biosynthesis in gastrointestinal cancer cells and associates with cancer cell motility Costa AF 2023 Apr 19
  • PubChem
36125302 The Sialyl Lewis X Glycan Receptor Facilitates Infection of Subtype H7 Avian Influenza A Viruses Guan M 2022 Oct 12
  • PubChem

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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