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mannosidase, beta A, lysosomal

Summary

Gene Symbol

Manba

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

110173

PubChem

110173

Alliance of Genome Resources

MGI:88175

Annotation

Keyword

3D-structure
Disulfide bond
Glycoprotein
Glycosidase
Lysosome
Proteomics identification
Reference proteome
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8K2I4	Lysosomal beta A mannosidase Mannanase
A0A0R4J092	Lysosomal beta A mannosidase Mannanase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
oligosaccharide catabolic process	IDA	3447593
metabolic process	IEA
glycoprotein catabolic process	IBA IDA	16377659 3447593

GO Hierarchy

biological process

metabolic process

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular space	IDA	19710420
lysosomal lumen	IDA	29773673
lysosome	TAS	3447593

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
hydrolase activity	IDA	19710420
hydrolase activity, acting on glycosyl bonds	IEA
mannose binding	ISO
beta-mannosidase activity	IBA IDA IMP ISO	16377659 30552791 33441424 3447593
hydrolase activity, hydrolyzing O-glycosyl compounds	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on glycosyl bonds

hydrolase activity, hydrolyzing O-glycosyl compounds

mannosidase activity [inference]

beta-mannosidase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

mannose binding

small molecule binding [inference]

monosaccharide binding [inference]

mannose binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3633	beta-mannosidosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	181517	WB:WBGene00007904
Drosophila melanogaster	40524	FB:FBgn0037215
Callorhinchus milii	103177724		CALMI13433
Danio rerio	393128	ZFIN:ZDB-GENE-040426-721
Astyanax mexicanus	103036309		ASTMX18110
Ictalurus punctatus	108263548		ICTPU27142
Electrophorus electricus	113585864		ELEEL36121
Salmo salar	106607245		SALSA67596
Gadus morhua	115544447		GADMO49298
Oryzias latipes	101166673		ORYLA10778

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