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serine palmitoyltransferase small subunit B

Summary

Gene Symbol

SPTSSB

Aliases

ADMP
androgen down regulated in mouse prostate
small subunit of serine palmitoyltransferase B
ssSPTb

Organism

Homo sapiens (human)

External Links

NCBI Gene

165679

HGNC

24045

KEGG Gene ID

hsa:165679

PubChem

165679

Alliance of Genome Resources

HGNC:24045

Annotation

Keyword

Endoplasmic reticulum
Reference proteome
Sphingolipid metabolism
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6ZWB5
Q8NFR3	Protein ADMP Small subunit of serine palmitoyltransferase B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ceramide biosynthetic process	IBA ISS
sphingosine biosynthetic process	IDA	19416851
regulation of serine C-palmitoyltransferase activity	IBA ISS
endoplasmic reticulum organization	IBA ISS
sphingolipid biosynthetic process	ISS TAS	19416851

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

sphingosine biosynthetic process

amide metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

amide biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

sphingosine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

diol biosynthetic process [inference]

sphingosine biosynthetic process

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

diol biosynthetic process [inference]

sphingosine biosynthetic process

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

sphingosine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

endoplasmic reticulum organization

biological regulation [inference]

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of transferase activity [inference]

regulation of serine C-palmitoyltransferase activity

Displaying **all 2** entries
GO Term	Evidence Code	PMID
serine C-palmitoyltransferase complex	IBA IDA IPI	19416851
endoplasmic reticulum membrane	NAS	33558761

GO Hierarchy

cellular component

protein-containing complex [inference]

endoplasmic reticulum protein-containing complex [inference]

endoplasmic reticulum palmitoyltransferase complex [inference]

serine C-palmitoyltransferase complex

catalytic complex [inference]

transferase complex [inference]

palmitoyltransferase complex [inference]

endoplasmic reticulum palmitoyltransferase complex [inference]

serine C-palmitoyltransferase complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	19416851
serine C-palmitoyltransferase activity	IBA IDA	19416851

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

C-acyltransferase activity [inference]

C-palmitoyltransferase activity [inference]

serine C-palmitoyltransferase activity

palmitoyltransferase activity [inference]

C-palmitoyltransferase activity [inference]

serine C-palmitoyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K26384

Name

serine palmitoyltransferase small subunit

References

19416851

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0060891	Parkinson's disease 19A	DisGeNET
DOID:0060895	Parkinson's disease 4	DisGeNET
DOID:0060896	Parkinson's disease 23	DisGeNET
DOID:14330	Parkinson's disease	DisGeNET

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP012370
Gene Name: serine palmitoyltransferase, small subunit B

Ortholog

Displaying entries **1 - 10** of 67 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	5740534	FB:FBgn0085223
Drosophila melanogaster	5740555	FB:FBgn0085322
Petromyzon marinus	116954546		PETMA01085
Callorhinchus milii	103175523		CALMI01254
Latimeria chalumnae	102357274		LATCH09292
Lepisosteus oculatus	102683675		LEPOC04169
Danio rerio	678546	ZFIN:ZDB-GENE-060421-6887	DANRE08676
Ictalurus punctatus	108280592		ICTPU15058
Salmo trutta	115163965		SALTR98098
Oreochromis niloticus	100694975		ORENI17705