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Mucin 16
Summary
- UniProt ID
- A0A140LJ72
- Gene Symbol
-
- Muc16
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0001488
- Re-Glyco
- A0A140LJ72
Annotation
- Keyword
-
- Proteomics identification
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| GO Term |
|---|
| negative regulation of interleukin-6 production |
| negative regulation of epithelial cell proliferation |
| negative regulation of wound healing |
Sequence
MGEEDVACSAHRHRHRYLLTLTTSLLLAYGPASAFQEPHSSSGPMTSVLRPIPKTNTRKLDTSTTVTASTLHWRSNIPSKLAAMKGTRNSKKAVNIINSTSSTPDVTFGSVLLKTTLSTKIPETTGKSTGYPSMTTSNFTRTETHNGTALNSTLLSDTSTTVTVAETNITEIISTTEHTPNFTEVPFTNSVLVSRTESTNNSISYPITNQVIKAEEISTGMPTGPPNSIISKEITTSQIEHFVVTPNIIASQGIPATTSGAGMHSSVSHNYSLLETSTLLKSDKVPSRTNSSPLEGISSESSWKTTVRTSSSSPVKLSSQRHLPITHHTTKQSWTTAQIQSSTLEEVDLITEYSLNHTEVPMNLSLLEPSTKDMSTGNISFTTLHESISEDTSFGITIGTPSSSITSKLQQLSNSHNGHSVVTSSMVTSKSPSTSASINVTNSSRVQTFPHPEAMDPPKNITSGPQTHNLWEESVFEDSTMPHESHSPSAISSIRDTHSTSFTGSVAYVITVSKDTIPTDLSTRSEPVISSIQSLNGSPQKSFNIAQVSKISQMTSVSSVTKGNKKNGSSTPKLKHTIIPTPISSEHEYFTTILARSEDTTLSSPQSISFTTAEIGKPTDSSLMKAWKSSSKYEDIHSTKEHRISQTNVPTTLSLVTSVAKDISAGSTFLSKLHHSISEDTSTGISTKYSRSTTTTESEQTATSHREHTVVTSNMVTSKDLSTTSSNTETQHSGTQTFTLSESMVNSTNINPATTLRTNSVWEGSMPTSSTRTPDEAPSHSPVSANADRYSTPSSVSASIVTISKEPNPTRLYVIPKSVTPSIPSSNSTQFSKIPQTTSVSLLGSVEGMKKSTFKHAITPISVSLEKESFTTILPTMEQARLSPSQSVSSERTDTERGISFPLRTAWTDFSTSEQINTSTEYSTSHTELSTSPSPLESRTGLTSADSISISDLQSTLQDTSSGTSISIPASTVSAESEEMKSRPMGLYPVISDILTYPDSSSTVSVKGTHSSGTHTFPHSESRAPFNNLASASWTPTPEKGTISTDSTKTQESLSLTADTYMPHTHSSHSPDSVVSFFTSSKDSIPTDSYTSLGPVTVYVPSWSSTSQSSSNTVHASQMSQMNTFSSVTSGSNMGDSHSVPEFKYTTTSVSVPSELSTEKKTFPTTLPTTEVATLIPTKSTSYENTSSGTKTVTLLTTLTQANSPEKVHSSTDFIRHPSEVPNSSSTPVSSTRSMSPDNAILPTLWHFTSEHTGFTPEDMTSGTVTKCYDSNTITESQEVSTSQIRDSNVTSNIALSLKTSTMSSESDNFMSFSPAPTITETSTFVSQSYEVPSIATFSTLKGSPLGNSPGYLNESSLTSSVTSTGENNTPSPSPVVSVFTSSKEKITTRLDKPLHNLSTSFSNWTTNTHTSQETSQATEFSQTSSASSVNSEIITEVSSSIPQPKFSVSESIRAGRTLTRSPLYSSESEDITPGSISRLITYPSTEHIGLTSIFGTANSGSLLSDSLSRDIAATVPMKEFSSPEPQTSPHLSWISESHSFEEQSQTSSLSKGKHTSTDPTSTMIEKTTLSPVTSTSQGQNVSSLDFLAALVTSIHETNSNGQDTSATSGSNSIQSLDTIGLSTPGSSYNMKTFQTSHISPKNPATRVETDSPAMHPQGTVLVNSVPSRITEIMISQSNWDTISPSMPLSSPVHAETQKAFPITSIEQETTRSEDTDLMKKHSSGLLTVSTSTYPGISRTEANSTDTTSTSNSVSFAKTTDTSVGNASSSSTLFFPRTDISQVVNVEESSNITTLLNTSDPITYSGALSTVTQTFLHSDSISHPSSSELLSWTDSPLHEATSSVNSIETIHTSSFPVTSPSEGQGLFFPSSEETTTEELDTNLAFFKTSFPSWSNSELAISKDTRTSQKSYNSTKTEVSPVNITTSEPPAQYTVSPETLSADSTASSLLIIPTKISASASPLLPQRSNSTSFPKTSFPTSELFKTTDILDRSLETGISLPPNLRSTSLEILGLSEVVTDTEKHHSSSSFTVTNVNTITVGHELSSSVSTLSESSRDADTSGTPPSVWVTTILTSLPNHLETTRSNTDSFSHLTSGLRDTSISLQTNKPSPLESTLHLPSSETDVATAVNIPTPYQSPSPKFTDIPIATATILNPSSSIVESTGATSFPEYDFTMLSRENIHVPRTDILPSAETTLIDTTATLSPRGMTFFATTSNPTGISAVTSESSHSMIQSSHLFATIVKKPPSSISTPLPYPISTTTDTAASSSLQRITTPSEMEDGMQYHTDISNGAVHGDTAGLGKGSLASTSSANHKDLTTEGTVKADTTTRALKASSIFTPNTKMSTTISTPPTHIKTSKKTTNINTTEMIITASDASHNLLEMAPSFSTGLRENISMVARTSPSSYSRKPEITIPQIPSLKTKTIPNVNTLTVSSAESDTISWITHALEITSAIAKTTKNASQVELDSKVSTATSSRGKDRSTLSTAAVSSAIPDLASIEQEDRLFGPTISISSSIPDMKNLEGYSSKEDIGTSKPILTHSPSEPYNTISLISHAGGKTDSPMSTIAVSPDVTEIMRPLFTSSGRRIHTRNPTQGQSVTTSWITHPGTEATSRVLTTTISPNNQEVETSKSANPSKLQTTTSLITDSKEQPSFTMSTLAVSLGVIEGTPSPVINRGTERNSRTATLDFFLDLPETTTSWTTNPEKEAISGILTTKYAPSVTDRMTTINLNHTPPEPQNITSLATHYVRHSLITSTKVVHPDIEEVKPSQVTSSVTESHVMTSNMAFSPGKHETINPFVTHPRRKVTSGILTAAISPSVTNMMTFTPVKHSPSEPQPIESLDTNAEGHPSASMSTQALSPGMREMMIPQAPNYGRETYITTSTLPVSVGQIESTASLVTHAEKEATLGVLPTTVSTISPNMMASTELMSSGPHTTASLVTHNGEQHSSDMSTLPASSGITKIKQSLDTTTGKESQSVITTLAVSLGIPKTKSINTTSNVPDMMISKSWNHTSSNVHTITSLVTHAGTQSSFSKSTKAASPSITKLTASLFTDTDTENVAITALPTSSGQMEKRAPSVTKPEKETISDVLSITTSTSVQQMMISPTVIPSEPHTTVSFDTHVGGQPSSTMSILPVTSDSTKIISSLGTRSGTESHSVTSTMDISQGQLETTASGDTHTEREGNSLTLSTVISTSAPDIMTSTNENQTSSDRQTIISLLTLAGEDTSLSVPSQGGSPGIMKVTPSLFTDVGTEGYAITSTLPVFSGQPDTRTPWDKHSETKVTTVVLPTTISTSVPEIMTSPTPIPSEAHTTVSLITHAGGAPSLAMSTLPVSGALTENIPSKVTYRGKEGNSVTSALDVSWDQKESTAPWVSYQAKEGPSEVLSTNISTRAPDMVFSTNKNQTSSDTQTMTSLITQTGEQTSLSESTQGVSSAITKMTQSIFNDLGTESYEMTSTLPASSHQSETRTKWITHSKIEQMSGVLSTTNSSSAPKMMTSTPITSELHATVSLVTHVGAQHSSTMSALTASPGKTEIMPSEQTHTGTEIHSVTSTLDVSAGQEELTTAWVTQSEKERTSGVLSTAISLSVPNMTSATLNNNSLDIRTITAFMKHPAGKSSLSMSTEGISPRITEVTPSLFTDLGTESYAMTSTMPASSGQSETRKSWNTNSEMEATPGVLSTSITTNVSEMITSSTSFPSEPHTTVSLVTQLGGNSSSPMSALPASPGRTEIKSSLVTYPDTESYSVTSTLDIFTGEAESTTPASTHTGREGTSETVTRNTSTSVPDMMTSITKRHSASNTQIMESLVDSMEIHHGGKPSLSVSSQHVTPDITEVTQSLFTNLGYERNTVIPTLPVSPGQPDTQATWVIHSEKEATSRVLPTSTSPHVSEPKASPTDIPSEPQNTVSLLTQVGGQSSSAMYILQTSTGRTKIKPSVVTQPGTESFAMLSTPDISQGQTESATPWPTHPPKKGTSEVLSTTISNSSPATMTSITKNQTSFDSQNITSFITHAEVQPSLSVSMQDISTGKAKVSTSQFTDLGRENCAMTSMLPALSGQVETKAPWDTNSEMEGIFGPVSTIISSSVPEMMTSPNVIPSEPHTKVPLSNHDVGQPTSIMSTLHVLPSIPEFKPKLDTSYGAESQSLTSTMGIFVDQARSTNTWATHTGRKDTSGIESRLISTSAPEMMTSITKNQTSSETKTITPYVIQAGGESTSGTVSKIISTSAPEKMNSVTKNQTSSDTQITHAGEQPSLSVSTQDISPRITEVIPSEFTDIGPKRFAMTSTLPASPGQAETNGTITPWNSNSEMEATSGPLSTTILPGVQEMMTSPSVFPSEQQTTVPLVSHYVGQPTSVMSTLPFSPGRTENMPSLVSSSGIQSHSVTSIKDTSVNKAVSTTTWATHTGRENTSGTESTLISTSAPETITSITKHQTSADTQTIMSFITHPAGQPSLSVSPYGASPGITVVTPSQFSDLGTESYAMASTLPASPGQAESKTPWDTHSEMEATSGPVPTTISPGVLETMTSPTVIPSEPPTKVPLVTHVVGPSTSSMSTLHVSPGIPEITPSVVTSYGPESHSATSTQVISIDQAGSTTTWSAHTGRGNTSGTESTLISSSGSEMMTSIKKIQTSSETQTITSFITHAGGESTSGTVSTVISTSAPEMVNSLTKNQTSSDTQITHAGEQPSLSVSTQDVSPRITEVTPSEFTDLSSNNYAMASTLPSSPGLEETKTPWNSNSEMEATSGHLSTTISHGVPQMMTATTVIPSQPHSTLPIVTHIPGQQTSVMSIFPFSPGRTERMPSLFPSPSRENHLVSSTQDISIDQAVSTTPWPNHTGNKITSGTKSTLISTSSAETMTSITKNQTSSATQTSFISHAAGESSLSGSTYGVSFGITQLSPSQFTDLGTKNYAMTSTFPASPSEIETKAPWNTNSKMEASSGPLSTTISSGVSEMRTAPTVASSETHTKVALVTHIIGQLTSVGSTLPFSSGKIENMPSLVSSSGIQSHSGTSIQDTSVNQAVSTTTWATHTGRENTSGTESTLISTSAPETITSITKHQTSSDTQTITSFITHSAGQPSLSVSPYGASPGITVVTPSQFSDLGTESNTMTSTLPASPGQAESKTPWDTHSEMEATSGPVPTTISPGVLETMTSPTVIPSEPPTKVPLVTHVVGPSTSSMSTLHVSPGIPEISPSVVTSYVPESLSVASTMSIFIDQAGSTTTWSAQTGRGNTSGTESTLLSTSAPELMTSLTRNPNSSETEAITSFITHPGEESTSGTVSTIISSRAPDVMTSVTKNQTSSETQTITSFITHHGGQPSLSVSTQGVSPRITVVTPSEFTDLSSKSYAMTSSLPTSPGLEETKTPWVSSSELEATSGPLSTTILPGVQEMMTSPSVFPSEQQTTVPLVSHYVGQPTSVMSTLPFSPGRTESIPSVFPSSGTESHSVTSTQDTSIDQAVSITPWSTLTGRGHTLGTESPLISTSAPETITSITKNGTSSDTQTITSFITHHGGQPSLSVSTQGVSPGITEVTLSQFTDFSTKNYAMTSTLPASPGQAESKTLWNTNSEMETNSGPLSSTISSVVQEMMTSPTVISSEPHTNVPLVSSDVVQSSSSMSTLSVSPGTPEITPSVVTSYVSESHSLPSTLPVSSSQSKSPAQWITHTGHEGASGNLSPTISPSVPEIMTVTTLNHTLPKSLTITSLSTQVGVQPSLNRTTTAFSPSIPKLTSLSTNLGIESHHTTVSLSPSLSETIASLVTHSQKEASLGVLTTTIPSTILDTMTSPSLLTSESYTTISLTTPLEGQPSSSMSTLAVSPGVTEKIPLLVTSSSTNTHSVSSTLHASPGQLETPALMVTPPEREATSSILRTDISPSIPDLMASKTHNPSEHTTISSVTYVGGQSSPSISTLTKFPSIKDIMTPLATTSVVETHKTAPTLSVPADQRETTALWVIHSGKELMSTVSSPPTLPGDSERTETWLILSAKTSTPHPTITSTFSYNDITSSVSEVETSSATTLSSGASEEAASLSGHTGTETSTSTLTVTPSSTSPGTTGLQPSSPSKEYTLTMSSSLPVFPDHSTTSKFGIATSKNIETSPSLSTVRLSDFVSDVISPAMTLSSESSTHAPTDLETTRETTHSATTSSKPTGDKTTTSLHESSSALLTTRRISTLSPENVTSRPSYHHQYWTPKTSTTNPSLVPFTLNFTITNLHHTEGMASQGSEIFNSTERILNSLLKPMFKNSSIGHLYSGCRLITLRPEKDGTATGVDAVCTLHSDPLGLQLDREKMYWELSHNTQGVTKLGSFTLEKDSLYINGYTHQIQSITSPMPLSSLVPFTINFTITNLKYEEGMNHPGSWKFNATERILQRLLWPLFNKTSISLRYSNCRLALLSERVFWELCNLTNNVTQLGPYTLDKNSLYINGYTHQIQSITSPTAGPVLEHFTINFTIINLKFEEDMSHPGSRKFNITERTLQRLLRILFKKSSVGALYSGCKLSLLRPENDGAGTGVDAVCTHYPDPTGLGLDRKMLYGEISRLTYGVKRLGPYTLNDKSLYVNGYTHQIVATTTQMAMMTIASMGMINNSPSPTAGSGLVPFTINFTVTNLKYVENMHHPGSRKFNTTERILQKLLKALFSKTSVGPLYSGCRLILLRLEHNGTATGVDAICTYHPNISNQGLDRERVYWELKRLNITQLGPYIVDENSLYINGYTQQILSTTSRPSVMATVSEGMPNISSTPTATSPVLVPFTINFTITNLEFKKDMGRPGSRKFNVTERTLQSLLRPLFIKTSVGQLYSGCRITLLRPEKNRAATGVDATCTYHLDPAGHRLESEQIYEELSNLTQSVTQLGPYILDQNSLYVNGYTDQILATTPRALSSALLRCTLNFTITNLPHTNDMWVPGSAKFNKVEKILKLLLKPLFQNTSVGLLYSGCRLTSLRPKKDGEATRVDMVCTYHPNTTGTGLDREQLYLELEQLTHNITQLGPYSLDQNSLYVNGYTHQTAVTSPSKSPLEIFTFNFTITNLLYTENMQPPGSKKFNTIEKILQGLLGSLFKNTSIGPLYTGCRLTSLSSRKDGKATEVDTVCSYYADHMGPGLATEQLYLELSNLTHGVTKLGPYTLDQDSLYVNDYTYSASSIFHNTSSLVPYSTNNSTGNGTVMVSITLNFTITNLHYTEEMGHPGSLKFNSTKWTLHYWLDTLLNKTSIAPLYSGCRLASLRSDDHRAATEVDVICNFHSYSMSPGVNQDQLFWELSHGTHGITHLGPYTLDQNSLYINGNSFGAAAPNTTTGELSEELFTVNFTINNLRYSADMSQIGSPKFNITDTLMQHLLGPLFQRSSLGPLYTGCRVATLRSMKNGAQTQVDVLCTYRRVFNSQGLPAKPIFYDLSWQTHGITKLGPYSLDKDSLFINGYNEPGPDVPPTTPEPATTILPSPTTSLQPESNTVMWHKPETFTINFTISNLPYSVDMISGSAIFNSTENVLQRLLGPLFQNDSFNSSCRLTSLRPEKNGMFTGVVTTCTYQNDPAHPGMDIQGLYSELSHLSHGVTQLGNYTLEEHSLYVNGYPILGPDILTTTPEPSTTILPFTLTSVQPESTTARAHHLKTITINFTISNLPYSAEMNYSSAMFNSTESVLQHLLRPLFQNNSFNASCRLTSLRPEKNQNSTNVNVICSYQHYSAHPGLHTQELYSELSHLTHGFTQLGNYTLDKDSLYVNGYNEIGTKEPTTNPETATTMLPSPSILVQTESTTAVGYHLKTVTVSFTISNLPYSAHMNNGSAVFNSTETVLKHLLEPLLHNGSFNSSCRLDSLRPEKNGTATAVEAICTYYHNAANSGIDTQELYSELSHLTYGITQLGNYTLDQESLHVSGYNEPHPEEPPTTPEPTTTMQPSPSTALHPEPTTGHHLKILTINFTISNLPYLSNMSNGSAMFNSTESVVQYLLSHLFQNGSFNSSCTLDSLRSRKNGTATGVNVICIYHHDPENPEMDIHGLYLEINNLTHGITQLGNYSLDNGSLYINGYNEHGVEELYTAPESPSTIVPSSSTFVKGEPTVAMGNLKTFTLNFTISNLPYSTDMSSGSAMFNSTERILQHLIRPLVQNESLYSNCRLASLRPKKNGTATGVNAICSYHQNPDHPELDTQELYTKLTQLTQGVTQLGSYMLDQNSIYVNGYTHQTAETTSSGYVPLNITIQGKYQLNFCIINWNLNNTDPTSSEYITLERDIEDKVTTLYTGSQLKEVFQSCLVTNMTSGSTVVTLEALFSSHLDPNLVKQVFLNKTLNASSHWLGATYQLKDLHVIDMKTSILLPAEIPTTSSSSQHFNLNFTITNLPYSQDIAQPSTTKYQQTKRSIENALNQLFRNSSIKSYFSDCQVLAFRSVSNNNNHTGVDSLCNFSPLARRVDRVAIYEEFLRMTHNGTQLLNFTLDRKSVFVDGYSQNRDDDVMKNSGLPFWAIILICLAVLLVLITCLMCCFLVTVCRRKKEGDYQVQRHRLAYYLSHLDLRKLQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 6447 |
|
|
||
| 6635 |
|
|
||
| 6650 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| O-linked glycosylation of mucins | Mus musculus |
| Termination of O-glycan biosynthesis | Mus musculus |
