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MIRAGE
Fibroblast growth factor receptor
Summary
- UniProt ID
- A0A3Q1LRU7
- Gene Symbol
-
- FGFR2
- Organism
- Bos taurus (domestic cattle)
External Links
- Re-Glyco
- A0A3Q1LRU7
Annotation
- Keyword
-
- ATP-binding
- Apoptosis
- Cell membrane
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasmic vesicle |
| receptor complex |
| Golgi apparatus |
| plasma membrane |
| GO Term |
|---|
| apoptotic process |
| positive regulation of cell population proliferation |
| transmembrane receptor protein tyrosine kinase signaling pathway |
Sequence
MSLIEPPTKYQISQPEVYVAAPRESLELRCLLRDAAMISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTAARNVDSETVYFMVNVTDAISSGDDEDDADGSEDFVSENSNSKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENDYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPVREKEIPASPDYLEIAIYCIGVFFIACMVVTVILCRMRNTTKKPDFSSQPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKEKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMAFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQLLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHRNGSVKT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 51 | N-linked (GlcNAc...) asparagine |
|
||
| 91 | N-linked (GlcNAc...) asparagine |
|
||
| 196 | N-linked (GlcNAc...) asparagine |
|
||
| 209 | N-linked (GlcNAc...) asparagine |
|
||
| 233 | N-linked (GlcNAc...) asparagine |
|
||
| 265 | N-linked (GlcNAc...) asparagine |
|
||
| 286 | N-linked (GlcNAc...) asparagine |
|
||
| 297 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR2b ligand binding and activation | Bos taurus |
| FGFR2c ligand binding and activation | Bos taurus |
| FRS-mediated FGFR2 signaling | Bos taurus |
| Negative regulation of FGFR2 signaling | Bos taurus |
| PI-3K cascade:FGFR2 | Bos taurus |
| PI3K Cascade | Bos taurus |
| PI3K/AKT Signaling | Bos taurus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Bos taurus |
| Phospholipase C-mediated cascade; FGFR2 | Bos taurus |
| RAF/MAP kinase cascade | Bos taurus |
