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Replicase polyprotein 1ab

Summary

UniProt ID

A0A455LHT0

Gene Symbol

ORF1ab

Organism

Equine arteritis virus

External Links

Re-Glyco: A0A455LHT0

Annotation

Keyword

Endonuclease
Helicase
Host cytoplasm
Host membrane
Lyase
RNA-directed RNA polymerase
Ribosomal frameshifting
Serine protease
Thiol protease
Transmembrane helix
Viral RNA replication
Zinc-finger

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
host cell membrane
host cell perinuclear region of cytoplasm
membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 5** entries
GO Term
proteolysis
DNA-templated transcription
viral protein processing
viral RNA genome replication
viral translational frameshifting

Displaying entries **1 - 10** of 16 in total

1

2

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GO Term
lyase activity
serine-type endopeptidase activity
zinc ion binding
double-stranded DNA helicase activity
forked DNA-dependent helicase activity
RNA binding
RNA helicase activity
RNA-dependent RNA polymerase activity
cysteine-type endopeptidase activity
four-way junction helicase activity

Annotation information from UniProt.

Sequence

MATFSATGFGGSFVRDWSLDLPDACEHGAGLCCEVDGSTLCAECLRGCEGMEQCPGLFMGLLKLASPVPVGHKFLIGWYRAAKVTGRYNFLELLQHPAFAQLRVVDARLAIEEASVFISTDHASAKRFPGARFALTPVYANAWVVSPAANSLIVTIDQEQDGFCWLKLLPPDRREAGLRLYYNHYREQRTGWLSKTGLRLWLGDLGLGINASSGGLKFHIMRGSPQRAWHITTRSCKLKSYYVCDISEADWSCLPAGNYGGYNPPGDGACGYRCLAFMNGATAVSAGCSSDLWCDDELAYRVFQLSPTFTVTIPGGRVCPNAKHVMICDKQHWRVKRAKGVGLCLDESCFRGTCNCQRMSGPPPAPVSAAVLDHILEAATFGNVRVVTTEEQSRPVPAPRARPSVNSSGDDKDPAPVPPVPKPRTKLVKPNPTQAPIPAPRTRPPGASAQEPPVNAETASASASKWRVAKTVYNSAERCRAELVQRARSVGDVLFQALPLKTPAVQRYTMTLKMMRSRFSWHCDTWYPLVAIACLLPIWPSLALLLSFAIGLIPSVGNNVVLTALLVSSANYVASMDHQCEGAACLALLEEEHYYRAVRWRPITGALSLVLNLLGQVGYISRSTFDAAYVPCTVFDLCSFAILYLCRNRCWRCFGRCVRVGPATHVLGSTGQRVSKLALIDLCDHFSKPTIDVVGMATGWSGCYTGAAAMERQCASTVDPHSFDQKKAGAIVYLTPPVNSGSALQCLNVMWKRPIGSTVLGEQTGAVVTAVKSISFSPPCCVSTTLPTRPGVTVVDHALYNRLTASGVDPALLRVGQGDFLKLNPGFRLIGGWIYGLCYFVLVVVSTFTCLPIKCGIGTRDPFCRRVFSVPVTKTQEHCHAGMCASAEGISLDSLGLSQLQSYWIAAVTSGLVVLLVCHRLAISALDLLTLASPLVLLVFPWASVGLLLACSLAGAAVKIQLLATLFVNLFFPQAALVTMGYWACVAALAVYSLMGLRVKVNVPMCVTPAHFLLLARSAGQSREQMLRVSAAAPTNSLLGVARDCYVTGTTRLYIPKEGGMVFEGLFRSPKARGNVGFVAGSSYGTGSVWARDNEVVVLTASHVVGRANMATLKIGDTMLTLTFKKNGDFAEAVTTQSELPGHWPQLHFAQPTTGPASWCTATGDEEGLLSGEVCLAWTTSGDSGSAVVQGDAVVGIHTGSNTSGVAYVTTPSGKLLGADTVTLSSLSKHFTGPLTSIPKDIPDNIIADVDTVPRSLAMLIDGLSNRESSLSGPQLLLIACFMWSYLNQPAYLPYVLGFFAANFFLPKSVGRPVVTGLLWLCCLFTPLSMRLCLFHLVCATVTGNVVSLWFYIAAAGTSYLSEMWFGGYPTMLFVPRFLVYQFPGWAIGAVLAVCSVTMLAAALGYTLLLDVFSASGRFDRTFMMKYFLEGGVKESVTASVTRAYGKPITQESLTAALAALTDDDFQFLSDVLDCRAVRSAMNLRAALTSFQVAQYRNILNASLQIDRDAARSRRLMAKLADFAVEQEVTAGDRVVVIDGLDRMAHFKDDLVLVPLTTKVVGGSRCTICDVVKEEANDTPVKPVPSRRRRKALPKGAQLEWDRHQEEKRNAGDDDFAVSNDYVKRVPKYWDPSDTRGTTVKIAGTTYQKVVDYSGNVHYVEHQEDLVDYVLGKGSYEGLDQDKVLDLTNMLKVDPTELSSKDKAKARQLAHLLLDLANPVEAVNQLNLRAPHIFPGDVGRRTFADSKDKGFVALHSRTMFLAARDFLFNIKFVCDEEFTKTPKDTLLGYVRACPGYWFIFRRTHRSLIDAYWDSMECVYALPTISDFDVSPGDVAVTGERWDFESPGGGRSKRLTADLVHAFQGYHGASYSYDDKVAVAVSGDPYRSDGVLYNTRWGNIPYSVPTNALEATACYRAGCEAVTDGTNVVATIGPFPEQQPIPDIPKSVLDNCADISCDAFIAPAAEAALCSDLEKYNLSTQGFVLPSVFSMVRAYLKEEIGDAPPLYLPSTVPSKNSQAGINGAEFPTKSLQSYCLIDDMVSRSMNSNLQTATMATCKRQYCSKYKIRSILGTNNYIGLGLRACLSGVTAAFQKAGKDGSPIYLGKSKFDPIPAPDKYCLETDLESCDRSTPALVRWFATNLIFELAGQPELVHSYVLNCCHDLVVAGSVAFTKRGGLSSGDPITSISNTIYSLVLYTQHMLLCGLEGYFPEIAEKYLDGSLELRDMFKYVRVYIYSDDVVLTTPNQHYAASFDRWVPHLQALLGFKVDPKKTVNTSSPSFLGCRFKQVDGKCYLASLQDRVTRSLLYHIGAKNPSEYYEAAVSIFKDSIICCDEDWWTDLHHRISSAARTDGVEFPTVEMLTSFRTKQYESAVCTVCGAAPVAKSACGGWFCGNCVPYHVGHCHTTSLFANCGHDIMYRSTYCTMCEGSPKQMVPKVPHPILDHLLCHIDYGSKEELTLIVADGRTTSPPGRYKVGHKVVAVVADVGGNIVFGCGPGSHLAVPLQDTLKGVVVNKALKNAAASEYVEGPPGSGKTFHLVKDVLAVVGSATLVVPTHASMLDCINKLKQEGADPYFVVPKYTVLDFPRPGSGNITVRLPQVGTSEGETFVDEVAYFSPVDLARILTQGRVKGYGDLNQLGCVGPASVPRDLWLRHFVSLEPLRACHRFGAAVCDLIKGIYPYYEPAPHTTKVVFVPNPDFEKGVVITAYHKDRGLGHRTIDSIQGCTFPVVTLRLPTPQSLTRPRAVVAVTRASQELYIYDPFDQLSGLLKFTKEAEAQDLIHGPPIACHLGQEIDLWSNEGLEYYKEVNLLYTHVPIKDGVIHSYPNCGPACGWEKQSNKISCLPRVAQNLGYHYSPDLPGFCPIPKELAEHWPVVSNDRYPNCLQITLQQVCELSKPCSAGYMVGQSVFVQTPGVTSYWLTEWVDGKARALPDSLFSSGRFETNSRAFLDDAEEKFAAAHPHACLGEITKSTVGGSHFIFSQYLPPLLPADAVALVGASLAGKAAKAACSVVDVYAPSFEPYLHPETLSRVYKIMIDFKPCRLMVWRNATFYVQEGVDAVTSALAAVSKLIKVPANEPVSFHVASGYRTNALVAPQAKISIGAYAAEWALSTEPPPAGYAIVRRYVVKRLLSSTEVFLCRRGVVSSTSVQTICALEGCKPLFNFLQIGSVIGPV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites