Prothrombin

Summary
UniProt ID
A0A5F7ZYG3
Gene Symbol
  • F2
Organism
Macaca mulatta (Rhesus monkey)
Annotation
Keyword
  • Acute phase
  • Blood coagulation
  • Cleavage on pair of basic residues
  • Disulfide bond
  • Gamma-carboxyglutamic acid
  • Kringle
  • Reference proteome
  • Serine protease
  • Signal
Gene Ontology (GO)
Displaying all 3 entries
GO Term
proteolysis
blood coagulation
acute-phase response
Displaying all 2 entries
GO Term
endoplasmic reticulum lumen
extracellular region
Displaying all 2 entries
GO Term
calcium ion binding
serine-type endopeptidase activity
Sequence
MGSRLGARGSVGGAQGAIFSSLPGTSASPDSPSQKPAGEGGLASCPRNGQDHLLLRPLSHDPPTAVFLAPQQVFLAPQQALSLLQRVRRASSGFLEEVFKGNLERECVEETCSYEEAFEALESSTATDAFWAKYTACETARTSRDTLAACLEGNCAEDLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRREECSIPVCGQDQVTVAMTPRSSVNLSLPSEECVPDRGRQYQGHLAVTTHGLPCLAWASAQAKALSKHQDFDSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFEYCDLNYCEEAVDEETGDGLGEDPDRAIEGRTATSEYQTFFDPRTFGLGEADCGLRPLFEKKSLEDKTEGELLESYIDGRIVEGWDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPSLFQAGYKGRVTGWGNLKETWTTNVGKVQPSVLQVVNLPIVERSVCKDSTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKNPLNKRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQEVIDQFGD
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
168 N-linked (GlcNAc...) (complex) asparagine
190 N-linked (GlcNAc...) (complex) asparagine
460 N-linked (GlcNAc...) (complex) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024