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Fibroblast growth factor receptor

Summary

UniProt ID

A0A8D0GLI8

Gene Symbol

FGFR1

Organism

Sphenodon punctatus (tuatara)

External Links

Annotation

Keyword

ATP-binding
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Immunoglobulin domain
Nucleus
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
epithelial to mesenchymal transition
positive regulation of MAPK cascade
positive regulation of vascular endothelial cell proliferation
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
positive regulation of endothelial cell chemotaxis to fibroblast growth factor
phosphorylation
positive regulation of blood vessel endothelial cell migration
positive regulation of neuron differentiation
regulation of macromolecule metabolic process

Displaying **all 5** entries
GO Term
cytoplasmic vesicle
receptor complex
cytosol
nucleus
plasma membrane

Displaying **all 6** entries
GO Term
ATP binding
receptor-receptor interaction
protein homodimerization activity
fibroblast growth factor receptor activity
fibroblast growth factor binding
heparin binding

Annotation information from UniProt.

Sequence

MFTWRCLILWAVLVMATLSTARPAPTLPEKVLPKAKIEVESYSAHPGDLLQLRCRLRDDVQSINWVRNGVQLLENNRTRITGEEVEVRDAVPEDSGLYACMTNSPSGSETTYFSVNVSDALPSTEDDDDDDDSSSEEKETDNSKPNPMAPYWTYPEKMEKKLHAVPAAKTVKFKCPSNGTPSPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENKYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFVCKVYSDPQPHIQWLKHFEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLKNVSFEDAGEYTCLAGNSIGISHHSAWLTVLEAIEDKPAMMTSPVYLEIIIYCTGAFLISCMVVTVIIFKMKSTTKKTDFNSQLAVHKLAKSIPLRRQVSADSSSSMNSGVMLMRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLILGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGMEYCYNPTHIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHDPLPDEPCLPKYPPQHANGGLNRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
76	N-linked (GlcNAc...) asparagine	UniProt
116	N-linked (GlcNAc...) asparagine	UniProt
224	N-linked (GlcNAc...) asparagine	UniProt
237	N-linked (GlcNAc...) asparagine	UniProt
261	N-linked (GlcNAc...) asparagine	UniProt
293	N-linked (GlcNAc...) asparagine	UniProt
314	N-linked (GlcNAc...) asparagine	UniProt
327	N-linked (GlcNAc...) asparagine	UniProt