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Nuclear receptor coactivator

Summary

UniProt ID

A0A8I6APA0

Gene Symbol

Ncoa1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: A0A8I6APA0

Annotation

Keyword

Activator
Methylation
Nucleus
Proteomics identification
Reference proteome
Repeat
Transcription regulation

Gene Ontology (GO)

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GO Term
positive regulation of transcription from RNA polymerase II promoter by galactose
regulation of thyroid hormone mediated signaling pathway
male mating behavior
cellular response to hormone stimulus
positive regulation of apoptotic process
positive regulation of neuron differentiation
labyrinthine layer morphogenesis
mRNA transcription by RNA polymerase II
estrous cycle
positive regulation of female receptivity

Displaying **all 8** entries
GO Term
chromatin
nucleus
plasma membrane
nucleoplasm
transcription regulator complex
RNA polymerase II transcription regulator complex
cytosol
protein-containing complex

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GO Term
protein-containing complex binding
DNA binding
chromatin binding
transcription coactivator activity
nuclear receptor binding
nuclear estrogen receptor binding
nuclear receptor coactivator activity
nuclear retinoic acid receptor binding
nuclear retinoid X receptor binding
protein dimerization activity

Annotation information from UniProt.

Sequence

MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSGMSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARANRQQSTDLNSGSSHSNSSSSQGSFGCSPGNQIVASVALSQGQAGSQSSNPSLNLNNSPMEGTGISLAQFMSPRRQANSGLATRARMSNNSFPPNIPTLSSPVGITSGACSNNNRSYSNIPVTSLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDNKEIASILNEMIQSDNSANEGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSASASTAMSVSGQAQGSASIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQMDPCNTNPAPVTKPAPEEVKLESQSQFSADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVPGVNIKSEILPASLQPTPARSAPRLNRLPELELEAIDNQFGQPGAGDQIPWANNTVTAINQSKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERFPPQQATPPLMMEDRPTLYPQPYSSPSPTAGLSGPFQGMVRQKPSLGTMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQAILNQFAANAPVGMNMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQIIQQQRAMLMRHQSFGNNIPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLATRSSMVNRGMAGNMGGQFGTGISPQMQQNVFQYPGSGLVPQAEANFAPSLSPGSSMVPMPIPPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQSQPAPAQPGVYNNMSITVSMAGGNANVQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSSTDLLKTEADGNQVSKKENPSAELADAITLETWRTSHDMVKSRTLEVRRGCGPWLFPSQPWHCGFLKSSLEFCMTTERPTCLLTGR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Cytoprotection by HMOX1	Rattus norvegicus
Endogenous sterols	Rattus norvegicus
Estrogen-dependent gene expression	Rattus norvegicus
HATs acetylate histones	Rattus norvegicus
LXRs regulate gene expression linked to cholesterol transport and efflux	Rattus norvegicus
LXRs regulate gene expression to control bile acid homeostasis	Rattus norvegicus
Recycling of bile acids and salts	Rattus norvegicus
Regulation of lipid metabolism by PPARalpha	Rattus norvegicus
SUMOylation of transcription cofactors	Rattus norvegicus
Synthesis of bile acids and bile salts	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

International Collaboration

Acknowledgements