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Fibroblast growth factor receptor

Summary

UniProt ID: A0A9F3W0B3
Gene Symbol: FGFR2
Gene ID: 103057830
Organism: Python bivittatus (Burmese python)

External Links

Re-Glyco: A0A9F3W0B3

Annotation

Keyword: ATP-binding Apoptosis Cell membrane Cytoplasmic vesicle Disulfide bond Glycoprotein Golgi apparatus Immunoglobulin domain Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase Ubl conjugation

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
skeletal system development	IEA	GO_REF
apoptotic process
positive regulation of cell population proliferation	IEA	GO_REF
regulation of cell differentiation	IEA	GO_REF
animal organ development	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

developmental process [inference]

anatomical structure development [inference]

system development [inference]

skeletal system development

animal gross anatomical part developmental process [inference]

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of developmental process [inference]

regulation of cell differentiation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 4** entries
GO Term	Evidence Code	Reference
Golgi apparatus	IEA	GO_REF
plasma membrane	IEA	GO_REF GO_REF
cytoplasmic vesicle	IEA	GO_REF
signaling receptor complex	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying **all 3** entries
GO Term	Evidence Code	Reference
fibroblast growth factor receptor activity	IEA	GO_REF GO_REF
ATP binding	IEA	GO_REF GO_REF
fibroblast growth factor binding	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

binding [inference]

protein binding [inference]

growth factor binding [inference]

fibroblast growth factor binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGLKSTWSYGRQPQTGTEKMFSWDSYCLICLVMITMAGFSLARPSDSLVGEDTTSEPGEPPTKYQISQPDVRSVLPGETLKLHCQGKGATTITWTKDGKRLVSNNRTVITGETLWIKDTTPRDSGLYACTVRVADSETLYFIINVTDVLSSGDDEDDNDASEDFVNDSNPIKGPKWTHTDKMEKRLHAVPAANTVKFRCPATGNPQPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCIVENIHGSINHTYHLDVVERSPHRPILQAGLPANISAIVGSDAEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLEVLKHSGINSSNAEVLKLYNVTEEDAGEYICKVSNYIGEANQSAWLMVQPDKAPIDERPYPTYPDYVEISIYCSGVLVIVSMVVAVILYRMRSTTKKSDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSNADAPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAMGIDKDRPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMEYSFDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSGPLEQYSPSYPDTRSSCSSGDDSVFSSDPMSYEPCLPKYQHINGSVKT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
105	N-linked (GlcNAc...) asparagine	UniProt
144	N-linked (GlcNAc...) asparagine	UniProt
248	N-linked (GlcNAc...) asparagine	UniProt
261	N-linked (GlcNAc...) asparagine	UniProt
285	N-linked (GlcNAc...) asparagine	UniProt
317	N-linked (GlcNAc...) asparagine	UniProt
338	N-linked (GlcNAc...) asparagine	UniProt
349	N-linked (GlcNAc...) asparagine	UniProt