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Extended synaptotagmin-2

Summary

UniProt ID: A0FGR8
Gene Symbol: ESYT2 FAM62B KIAA1228
Gene ID: 57488
Organism: Homo sapiens (human)

External Links

GlyGen: A0FGR8
PubChem: A0FGR8
The Human Metabolome Database: HMDBP07672
The O-GlcNAc Database: A0FGR8
O-GlcNAcAtlas: A0FGR8
Re-Glyco: A0FGR8

Annotation

Keyword: 3D-structure Alternative splicing Calcium Cell membrane Endocytosis Endoplasmic reticulum Lipid transport Lipid-binding Metal-binding Phosphoprotein Proteomics identification Reference proteome Repeat Transmembrane helix

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
lipid transport	IEA	GO_REF
endocytosis
obsolete endoplasmic reticulum-plasma membrane tethering

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport

vesicle-mediated transport [inference]

endocytosis

import into cell [inference]

endocytosis

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
endoplasmic reticulum membrane	EXP	PMID
endoplasmic reticulum membrane	TAS	Reactome
endoplasmic reticulum membrane	IDA	PMID
endoplasmic reticulum membrane	IBA	GO_REF
endoplasmic reticulum membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle membrane contact site

endoplasmic reticulum-plasma membrane contact site

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
calcium ion binding	IDA	PMID
calcium ion binding	IBA	GO_REF
calcium-dependent phospholipid binding	IDA	PMID
calcium-dependent phospholipid binding	IBA	GO_REF
phosphatidylethanolamine binding	IDA	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding

cell adhesion molecule binding [inference]

cadherin binding

lipid binding [inference]

phospholipid binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

phosphatidylinositol binding

cation binding [inference]

phosphatidylcholine binding

metal ion binding [inference]

calcium ion binding

quaternary ammonium group binding [inference]

phosphatidylcholine binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTANRDAALSSHRHPGCAQRPRTPTFASSSQRRSAFGFDDGNFPGLGERSHAPGSRLGARRRAKTARGLRGHRQRGAGAGLSRPGSARAPSPPRPGGPENPGGVLSVELPGLLAQLARSFALLLPVYALGYLGLSFSWVLLALALLAWCRRSRGLKALRLCRALALLEDEERVVRLGVRACDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGANTHLSTFSFTKVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDVPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVGNQIFQSRVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEKERLLDEWFTLDEVPKGKLHLRLEWLTLMPNASNLDKVLTDIKADKDQANDGLSSALLILYLDSARNLPSGKKISSNPNPVVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQDLEVEVRDEQHQCSLGNLKVPLSQLLTSEDMTVSQRFQLSNSGPNSTIKMKIALRVLHLEKRERPPDHQHSAQVKRPSVSKEGRKTSIKSHMSGSPGPGGSNTAPSTPVIGGSDKPGMEEKAQPPEAGPQGLHDLGRSSSSLLASPGHISVKEPTPSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLTIRHSSQRNKLIVVVHACRNLIAFSEDGSDPYVRMYLLPDKRRSGRRKTHVSKKTLNPVFDQSFDFSVSLPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVALASEELAKGWTQWYDLTEDGTRPQAMT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites