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Hepatocyte growth factor receptor

Summary

UniProt ID: A0M8S8
Gene Symbol: MET
Gene ID: 493669
Organism: Felis catus (domestic cat)

External Links

Re-Glyco: A0M8S8

Annotation

Keyword: ATP-binding Disulfide bond Glycoprotein Phosphoprotein Proto-oncogene Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
liver development	IBA	GO_REF
cell surface receptor protein tyrosine kinase signaling pathway	IBA	GO_REF
cell surface receptor protein tyrosine kinase signaling pathway	IEA	GO_REF
regulation of gene expression	IEA	GO_REF
neuron differentiation	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

semaphorin-plexin signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell development

developmental process [inference]

anatomical structure development [inference]

cell development

animal gross anatomical part developmental process [inference]

animal organ development [inference]

pancreas development

gland development [inference]

liver development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

positive chemotaxis

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

regulation of chemotaxis [inference]

positive regulation of chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

regulation of endothelial cell chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

regulation of endothelial cell chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

regulation of chemotaxis [inference]

positive regulation of chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

regulation of endothelial cell chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

semaphorin-plexin signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

regulation of endothelial cell chemotaxis [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of endothelial cell chemotaxis

Displaying **all 4** entries
GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
basal plasma membrane	IBA	GO_REF
signaling receptor complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

basal plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	Reference
hepatocyte growth factor receptor activity	IBA	GO_REF
ATP binding	IEA	GO_REF
semaphorin receptor activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

hepatocyte growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

hepatocyte growth factor receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

hepatocyte growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

hepatocyte growth factor receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

hepatocyte growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

hepatocyte growth factor receptor activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

semaphorin receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

hepatocyte growth factor receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKAPAVLAPGILVLLFTLVQKSYGECREALVKSEMNVNMKYQLPNFTAETPIQNVVLHKHHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMALLIDTYYDDQLISCGSVHRGTCQRHVLPPSNTADILSKVHCMYSPQADEESSHCPDCVVSALGTKVLISEKGRFINFFVGNTINSSYLTDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNRFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSTREEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNFRLDSHPVSSEAIVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCHDKCVQLEECPSGTWTQEICLPTIYEVFPTSAPLEGGTMLTVCGWDFGFRRNNKFDLKKTRVFLGNESCTLTLSESTTNMLKCTVGPAVNEHFNISIIISNGRGTAQYSTFSYVDPVITSIFPSYGPKTGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQTIPTEFPIKLKIDLANREMNSFSYQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVISVHETRRNFTVACHHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNPVFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSDSEAVLCKVPNDLLKLNNELNIEWKQAVSSTILGKVIVQPDQNFTGLIVGVISISIILLLLLGVFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPMLNSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNIDGEGDT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	Description	Source
45	N-linked (GlcNAc...) asparagine	UniProt
106	N-linked (GlcNAc...) asparagine	UniProt
203	N-linked (GlcNAc...) asparagine	UniProt
359	N-linked (GlcNAc...) asparagine	UniProt
400	N-linked (GlcNAc...) asparagine	UniProt
406	N-linked (GlcNAc...) asparagine	UniProt
583	O-linked (Man) threonine	UniProt
608	N-linked (GlcNAc...) asparagine	UniProt
636	N-linked (GlcNAc...) asparagine	UniProt
677	O-linked (Man) threonine	UniProt