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Obscurin
Summary
- UniProt ID
- A2AAJ9
- Gene Symbol
-
- Gm878
- Obscn
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Calmodulin-binding
- Cell membrane
- Cytoplasm
- Developmental protein
- Differentiation
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Lipid-binding
- Magnesium
- Metal-binding
- Muscle protein
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- SH3 domain
- Secreted
- Serine/threonine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| Z disc |
| sarcolemma |
| intercalated disc |
| M band |
| nuclear body |
| striated muscle myosin thick filament |
| extracellular space |
| plasma membrane |
Sequence
MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDITDGYRDWGPAGPQKHMCKCAGAKIARYLGSSCYRFLQYDKGVWHWLEAALDTRQGKGTSSCSLHEKPKLVFAKGQQAHSEVKAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKAAPVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPSRFIEDLRSQEATEGTMATLRCQMSKTAPVEWKKGSETLRDGGRYSLRQDGPVCELQICDLAVEDAGEYSCVCGQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEGTMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKALPPRFIEDLRSQEAREGTVATLRCRMSKAAPVEWRKGSETLKDGDRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSVKALPAKFIEDLRSQEAPESSTVTLRCKLSKKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWRLEVLEPPHDASVKAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASARLSVLALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPAPETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEDTSVEGSAHSAQDGADQQAASVLWRLLGSEALGPSPGDLPNTRQSEPPAFEEAASQIPGAASGTPEVSQPGTHKGLEQETTSSGSQGWTVPIRVEGTAWPGAGTGQLLLDVHSQVIMETTQRTYVCQAPDTGVTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDAENQVYRRKLHSFYDVQEEIGRGVFGFVKRVQHKGNKMFCAAKFIPLRSKTRAQAYQERDILATLGHPLVTGLLDQFETRKTLILILELCSSEELLDRLFKKGVVTEAEVKVYIQQLVEGLHYLHSHGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPSEPQYSKYGSPEFVSPEIIEQNPVSEGSDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPTAAHLSEDAKDFIKATLQRTPRARPSTSQCLAHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPSLGVARHLRGEASGASSSSSSSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEETEASMPTADAAVPASPQSAGPPASPGCVPRHSVISSLFYQQAGEGAERGNKTSGAKRHPARRRHLLKGGYIARALPGLREPLMEYSLLEEEAAREEQASLMTKTPSFETALRLPSSSVREVPGRSHSLDNPPVTTGPSPEACKEQLLFPPSTGLTHETTAKDRGHKEGFLQESVPFPPMSGDSRPGKQEGSSQDSCRGKPASSCHSELGSGSQEGCGPPSSQSLGSLPPQSLKKELSTSCGPLFSEQPQAAPFPTQVSPLLGSEKEPQDGSLSEGPVPVPSSSPGSASQVDASLDTEGLSEAGDTCDFTPPPQRPQEQATTRKFSLESRGGYAGVAGYGTFAFGGDAGGMLGQGPLWARMAWAVSQSSEEQDEAATESPQPLESLGPIAEASGVPLRTSPSLTPWEEVEQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRRVPKPIEQPESPGSETEAGQGLADFLEEAAWPWPGELGLRAGLEITEEPEEPGDLEALLGEAAVGRKRKWSPSRGLFQFPGRCLSGEEPVELGLRQRVKASMAHISRILKGRPEGPEREGPPRKKAGLASFRLSGLKGRDQELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVESCGPVTYIVQCCIEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSEQVLLGGPNHLASEEESSRGRPAQLLPSTKTFAFQMQIRRGRFSVVRQCREKASGRALAAKIVPYQPEDKTAVLREYEALKRLHHPHLAQLHAAYLSPRHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVTEYNLLKVIDLGNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPESSEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQCGWLTEEGPTGSRPTPVTFPTVRLRAFVREREKRRALLYKKHNLAQVR
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (12/13) signalling events | Mus musculus |
| NRAGE signals death through JNK | Mus musculus |
| RHOA GTPase cycle | Mus musculus |
| RHOQ GTPase cycle | Mus musculus |
