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ADAM metallopeptidase with thrombospondin type 1 motif 1

Summary

UniProt ID

A7MB07

Gene Symbol

ADAMTS1

Gene ID

512171

Organism

Bos taurus (domestic cattle)

External Links

Re-Glyco: A7MB07

Annotation

Keyword

Calcium
Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Repeat
Zinc
Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
extracellular region
basement membrane
extracellular matrix
cytoplasmic vesicle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
heart trabecula formation
positive regulation of vascular associated smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
positive regulation of G1/S transition of mitotic cell cycle
proteolysis
negative regulation of angiogenesis
extracellular matrix organization
ovulation from ovarian follicle
kidney development

Displaying **all 3** entries
GO Term
heparin binding
zinc ion binding
metalloendopeptidase activity

Annotation information from UniProt.

Sequence

MQRAVPAGFRKRTAGGDMGHKAPRARGLQPVPSPLLLLAAAAALLVVPGAHGRPAEEDEELVLPALERDPGLRTAHLRLDAFGRQLSLELHLDRGFLAPGFTLQTVGRRPEPDVQRSDPVGDLAHCFYSGTVNGDPSSAAALSLCDGVRGAFYLQGEEYFIQPAPAAATLSLAPAAAAAAAAAGEQQQARPQFHLLRRRRRGDGGAKCGVLDDETQLAGGAGPEGEDATVQWAPRDPAPQRPGHRTGTGSLRKKRFVSSPRYVETMLVADQSMAEFHGSDLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIYEEKKGPEVTSNAALTLRNFCSWQKQHNPPSDRDAEHYDTAILFTRQDLCGTQTCDTLGMADVGTICDPSRSCSVIEDDGLQAAFTTAHELGHVFNMPHDDAKQCAGINGLNRDSHMMASMLTNLDHNQPWSPCSASSITTFLDNGHGECLMDEPQLVIQLPSDLPGTLYDASRQCQLTFGEESRHCPDAASTCMILWCTGTSGGLPVCQTKHFPWADGTSCGEGKWCVNGQCLDQTDKEHFDTPVHGSWGPWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNIEDCPENNGKTFRMEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGTGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDHIIDSKNKFDKCGICGGNGSTCKKVSGSVTTAKPGYHDIVTIPTGATNIEVKQRNHRGSRNNGSFLAIKAADGTYILNGDFTLSTLEQDITHKGSVLRYSGSSAALERIRSFSPLKEPLTIQVLTVGNAFRPKIKYTYFVKKKKESFNAIPTFSEWVIEEWGECSKSCGLGVQRRLVECRDINGQPASECAKEVKPASTRPCADLPCPRWQLGDWSPCSKTCGKGYKKRTLQCLSHDGGVLSHESCDPLKKPKHYIDFCTVAECS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
723	N-linked (GlcNAc...) asparagine			UniProt
767	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
O-glycosylation of TSR domain-containing proteins	Bos taurus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

International Collaboration

Acknowledgements