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ADAM metallopeptidase with thrombospondin type 1 motif 1

Summary

UniProt ID

A7MB07

Gene Symbol

ADAMTS1

Gene ID

512171

Organism

Bos taurus (domestic cattle)

External Links

Re-Glyco: A7MB07

Annotation

Keyword

Calcium
Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Repeat
Zinc
Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
extracellular region
basement membrane
extracellular matrix
cytoplasmic vesicle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
positive regulation of G1/S transition of mitotic cell cycle
proteolysis
negative regulation of angiogenesis
extracellular matrix organization
ovulation from ovarian follicle
kidney development
heart trabecula formation
positive regulation of vascular associated smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration

Displaying **all 3** entries
GO Term
heparin binding
zinc ion binding
metalloendopeptidase activity

Annotation information from UniProt.

Sequence

MQRAVPAGFRKRTAGGDMGHKAPRARGLQPVPSPLLLLAAAAALLVVPGAHGRPAEEDEELVLPALERDPGLRTAHLRLDAFGRQLSLELHLDRGFLAPGFTLQTVGRRPEPDVQRSDPVGDLAHCFYSGTVNGDPSSAAALSLCDGVRGAFYLQGEEYFIQPAPAAATLSLAPAAAAAAAAAGEQQQARPQFHLLRRRRRGDGGAKCGVLDDETQLAGGAGPEGEDATVQWAPRDPAPQRPGHRTGTGSLRKKRFVSSPRYVETMLVADQSMAEFHGSDLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIYEEKKGPEVTSNAALTLRNFCSWQKQHNPPSDRDAEHYDTAILFTRQDLCGTQTCDTLGMADVGTICDPSRSCSVIEDDGLQAAFTTAHELGHVFNMPHDDAKQCAGINGLNRDSHMMASMLTNLDHNQPWSPCSASSITTFLDNGHGECLMDEPQLVIQLPSDLPGTLYDASRQCQLTFGEESRHCPDAASTCMILWCTGTSGGLPVCQTKHFPWADGTSCGEGKWCVNGQCLDQTDKEHFDTPVHGSWGPWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNIEDCPENNGKTFRMEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGTGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDHIIDSKNKFDKCGICGGNGSTCKKVSGSVTTAKPGYHDIVTIPTGATNIEVKQRNHRGSRNNGSFLAIKAADGTYILNGDFTLSTLEQDITHKGSVLRYSGSSAALERIRSFSPLKEPLTIQVLTVGNAFRPKIKYTYFVKKKKESFNAIPTFSEWVIEEWGECSKSCGLGVQRRLVECRDINGQPASECAKEVKPASTRPCADLPCPRWQLGDWSPCSKTCGKGYKKRTLQCLSHDGGVLSHESCDPLKKPKHYIDFCTVAECS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
723	N-linked (GlcNAc...) asparagine			UniProt
767	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
O-glycosylation of TSR domain-containing proteins	Bos taurus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

International Collaboration

Acknowledgements