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MIRAGE
Transferrin receptor protein 2

Summary
UniProt ID
B2GUY2
Gene Symbol
  • Tfr2
  • Trfr2
Gene ID
288562
Organism
Rattus norvegicus (Norway rat)
PubChem
B2GUY2
Re-Glyco
B2GUY2
Annotation
Keyword
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Receptor
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 4 entries
GO Term
plasma membrane
HFE-transferrin receptor complex
cytoplasmic vesicle
external side of plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
transferrin receptor activity
co-receptor binding
Annotation information from UniProt.
Sequence
MEQRWGLLRKVQQWSPRPSQTIYRRVEGPQLENLEEEDREEGEELPAQFCPMELKGPERLGSCPGRSIPIPWAAAGRKAAPYLVLTTLLIFTGAFLLGYVAFRGSCQACGDSVLVVGEDVNSEDSSRGTLYWSDLQDMFLRFLGEGRMEDTIRLTSLRERVAGSARMATLVQDILDKLSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVGADGSVQEQLPLEDPEVYCPYSATGNATGKLVYAHYGRREDLQDLKAKDVELAGSLLLVRAGITSFAQKVAIAQDFGAHGVLIYPDPADFSQDPHKPGLSSDRAVYGHVHLGTGDPYTPGFPSFNQTQFPPVESSGLPNIPAQPISADVADRLLRKLTGPVAPQEWKGRLSDSPYRLGPGPGLRLVVNNHRTSTPISNIFACIEGFAEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSSGFRPRRSLLFISWDGGDFGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLGDGKFHAKTSPLLVSLIENILKQVDSPNHSGQTLYDQVAFTHPSWDAEVIQPLPMDSSAYSFTAFAGVPAVEFSFMEDDRVYPFLHTKEDTYENLHKMLRGRLPAVVLAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRKEIYSSEQSDERLMRMYNVRIMRVEFYFLSQYVSPADSPFRHIFLGQGDHTLGALVEHLRMLRSDGSGAASSGLSPGLGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
235 N-linked (GlcNAc...) asparagine
334 N-linked (GlcNAc...) asparagine
535 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Transferrin endocytosis and recycling Rattus norvegicus
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0111030 hemochromatosis type 3
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025