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Toll-like receptor 2

Summary

UniProt ID

B3Y615

Gene Symbol

TLR2

Organism

Gorilla gorilla gorilla (western lowland gorilla)

External Links

PubChem: B3Y615

Annotation

Keyword

Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Inflammatory response
Innate immunity
Isopeptide bond
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 20 in total

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GO Term
inflammatory response
positive regulation of inflammatory response
positive regulation of interleukin-6 production
cellular response to type II interferon
positive regulation of Wnt signaling pathway
toll-like receptor signaling pathway
defense response to Gram-positive bacterium
defense response to virus
positive regulation of non-canonical NF-kappaB signal transduction
positive regulation of chemokine production

Displaying **all 6** entries
GO Term
Golgi apparatus
phagocytic vesicle membrane
membrane raft
cell surface
Toll-like receptor 1-Toll-like receptor 2 protein complex
Toll-like receptor 2-Toll-like receptor 6 protein complex

Displaying entry **11 - 11** of 11 in total

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1

2
GO Term
protein-containing complex binding

Annotation information from UniProt.

Sequence

MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNVDISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFLLILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRAAIKS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
114	N-linked (GlcNAc...) asparagine	UniProt
199	N-linked (GlcNAc...) asparagine	UniProt
414	N-linked (GlcNAc...) asparagine	UniProt
442	N-linked (GlcNAc...) asparagine	UniProt