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Toll-like receptor 7

Summary

UniProt ID

B3Y653

Gene Symbol

TLR7

Gene ID

574291

Organism

Macaca mulatta (Rhesus monkey)

External Links

Re-Glyco: B3Y653

Annotation

Keyword

3D-structure
Calcium
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
Metal-binding
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
lysosome
plasma membrane
receptor complex
endosome
endoplasmic reticulum
early phagosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 21 in total

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GO Term
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of macrophage cytokine production
cellular response to mechanical stimulus
cellular response to virus
positive regulation of non-canonical NF-kappaB signal transduction
canonical NF-kappaB signal transduction
positive regulation of canonical NF-kappaB signal transduction

Displaying **all 5** entries
GO Term
pattern recognition receptor activity
metal ion binding
double-stranded RNA binding
single-stranded RNA binding
siRNA binding

Annotation information from UniProt.

Sequence

MMFPVWTLKRQILILFNIILISKLLGARWFPKTLPCDVTLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPSGDSSEVGFCSNARTSVESYEPQVLEQLYYFRYDKYARSCRFKNKEASFTSVNESCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWVNHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNLILFSLSISVSLFLMVMMTASHLYFWDVWYIYHFCKAKIKGYQRLISPDCCYDAFIVYDTKDPAVTEWVLAELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVAYSQVFKETV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	Source
66	N-linked (GlcNAc...) asparagine	UniProt
69	N-linked (GlcNAc...) asparagine	UniProt
215	N-linked (GlcNAc...) asparagine	UniProt
361	N-linked (GlcNAc...) asparagine	UniProt
413	N-linked (GlcNAc...) asparagine	UniProt
523	N-linked (GlcNAc...) asparagine	UniProt
534	N-linked (GlcNAc...) asparagine	UniProt
590	N-linked (GlcNAc...) asparagine	UniProt
679	N-linked (GlcNAc...) asparagine	UniProt
720	N-linked (GlcNAc...) asparagine	UniProt