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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor
Summary
- UniProt ID
- F1LSG7
- Gene Symbol
-
- Fgfr2
- Organism
- Rattus norvegicus (Norway rat)
External Links
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| cell surface |
| nucleus |
| cytoplasm |
| Golgi apparatus |
| plasma membrane |
| cell cortex |
| collagen-containing extracellular matrix |
| receptor complex |
| excitatory synapse |
| GO Term |
|---|
| protein homodimerization activity |
| fibroblast growth factor receptor activity |
| fibroblast growth factor binding |
| ATP binding |
Sequence
MGLPSTWRYGTGPGIGTVTMVSWGRFICLVLVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEACVVAPGESLELRCMLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACAAARTVDSETLYFMVNVTDAISSGDDEDDTDSSEDFVSENRSNQRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCLVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEMDAGEYICKVSNYIGQANQSAWLTVLPKQQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVIFCRMKTTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLTQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYDPCLPQYPHINGSVKT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 102 | N-linked (GlcNAc...) asparagine |
|
||
| 142 | N-linked (GlcNAc...) asparagine |
|
||
| 247 | N-linked (GlcNAc...) asparagine |
|
||
| 260 | N-linked (GlcNAc...) asparagine |
|
||
| 284 | N-linked (GlcNAc...) asparagine |
|
||
| 316 | N-linked (GlcNAc...) asparagine |
|
||
| 337 | N-linked (GlcNAc...) asparagine |
|
||
| 348 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR2b ligand binding and activation | Rattus norvegicus |
| FGFR2c ligand binding and activation | Rattus norvegicus |
| FRS-mediated FGFR2 signaling | Rattus norvegicus |
| Negative regulation of FGFR2 signaling | Rattus norvegicus |
| PI-3K cascade:FGFR2 | Rattus norvegicus |
| PI3K Cascade | Rattus norvegicus |
| PI3K/AKT Signaling | Rattus norvegicus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Rattus norvegicus |
| Phospholipase C-mediated cascade; FGFR2 | Rattus norvegicus |
| RAF/MAP kinase cascade | Rattus norvegicus |
