Frizzled-2

Summary
UniProt ID
G5ECQ2
Gene Symbol
  • cfz-2
Organism
Caenorhabditis elegans
External Links
PubChem
G5ECQ2
Annotation
Keyword
  • Cell membrane
  • Developmental protein
  • Disulfide bond
  • G-protein coupled receptor
  • Glycoprotein
  • Neurogenesis
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Wnt signaling pathway
Gene Ontology (GO)
Sequence
MLLRISVLFLLLGSCGALFGKRQKCEQITIPLCKGIGYNMTSFPNSYGHEKQEEAGLEVHQFYPLVEVGCFQHLKFFLCTMYTPICQENYDKPILPCMELCVEARSKCSPIMAKYGFRWPETLSCEALPKMSDQMSTGNICAAPPDTPKKQHKGHHHKNQNQNQNQNHNYSPDGPEVGISKIDNEVIAGPSECQCTCNQPFQFVASEKSKVGNVTNCAYSCHSPALAESHSLVSNWMAFWSITCCVLASFTFLTFLIETDRFQYPERPIFMLAFCQLMVAVGFMIRYFVGHEEIACDSMRIKGADDNSGSLCFVVFLLTYFFGMAASVWWVILSLTWVLSAASKWSPEAISSFSFHFHVVGWCLPAIQTVLVIVFNAIDGDPITGICYVGNTDLQFQRIFVLFPLLVYFIVGVLFLVIGFCNLWSIRNEVQKQHPSLESAHKITQLMSKIGIFSLLYTIPSLLIICVLFYEQNHRSLWEQSQLCSCSPKQTIGDSSLIISLIKTCCMCILGWTSGFWVCSTKTLSSWKNAICCLGSSRSLPKYQPADILYAKSDMSSSQFYNTSLRHNHLYGGIPDKL
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
39 N-linked (GlcNAc...) asparagine
213 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
Asymmetric localization of PCP proteins Caenorhabditis elegans
Ca2+ pathway Caenorhabditis elegans
Disassembly of the destruction complex and recruitment of AXIN to the membrane Caenorhabditis elegans
Regulation of FZD by ubiquitination Caenorhabditis elegans
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Caenorhabditis elegans

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024