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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Mannan-binding lectin serine protease 2
Summary
- UniProt ID
- O00187
- Gene Symbol
-
- MASP2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O00187
- PubChem
- O00187
- The Human Metabolome Database
- HMDBP07788
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Autocatalytic cleavage
- Calcium
- Complement pathway
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Hydroxylation
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| complement activation, lectin pathway |
| complement activation, classical pathway |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| extracellular exosome |
Sequence
MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLILGGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIENIISDF
Glycosylation Sites
G00912UN
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0040084 | Streptococcus pneumonia | |
| DOID:0040085 | bacterial sepsis | |
| DOID:0050185 | erythema multiforme | |
| DOID:0050426 | Stevens-Johnson syndrome | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050700 | cardiomyopathy | |
| DOID:0050745 | diffuse large B-cell lymphoma | |
| DOID:0050873 | follicular lymphoma | |
| DOID:0060058 | lymphoma | |
| DOID:0060060 | non-Hodgkin lymphoma |
