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Repository for lectin-assisted multimodality data
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MIRAGE
Vascular endothelial growth factor receptor 2
Summary
- UniProt ID
- O08775
- Gene Symbol
-
- Flk1
- Kdr
- Gene ID
- 25589
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- ATP-binding
- Angiogenesis
- Cell junction
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Immunoglobulin domain
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| plasma membrane |
| cell junction |
| neuronal cell body |
| receptor complex |
| anchoring junction |
| cell periphery |
| endosome |
| early endosome |
Sequence
MESRALLAVALWFCVETRAASVGLPGDSLHPPKLSTQKDILTILANTTLQITCRGQRDLDWLWPNTPRDSEERVLVTECGDSIFCKTLTVPRVVGNDTGAYKCFYRDTDVSSIVYVYVQDHRSPFIASVSDEHGIVYITENKNKTVVIPCRGSISNLNVSLCARYPEKRFVPDGNRISWDSEKGFTIPSYMISYAGMVFCEAKINDETYQSIMYIVLVVGYRIYDVVLSPPHEIELSAGEKLVLNCTARTELNVGLDFSWQFPSSKHQHKKIVNRDVKSLPGTVAKMFLSTLTIDSVTKSDQGEYTCTAYSGLMTKKNKTFVRVHTKPFIAFGSGMKSLVEATVGSQVRIPVKYLSYPAPDIKWYRNGRPIESNYTMIVGDELTIMEVSERDAGNYTVILTNPISMEKQSHMVSLVVNVPPQIGEKALISPMDSYQYGTMQTLTCTVYANPPLHHIQWYWQLEEACSYRPSQTNPYTCKEWRHVKDFQGGNKIEVTKNQYALIEGKNKTVSTLVIQAAYVSALYKCEAINKAGRGERVISFHVIRGPEITVQPATQPTERESMSLLCTADRNTFENLTWYKLGSQATSVHMGESLTPVCKNLDALWKLNGTVFSNSTNDILIVAFQNASLQDQGNYVCSAQDKKTKKRHCLVKQLVILERMAPMITGNLENQTTTIGETIEVVCPTSGNPTPLITWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDGGLYTCQACNVLGCARAETLFIIEGVQEKTNLEVIILVGTAVIAMFFWLLLVILVRTVKRANEGELKTGYLSIVMDPDELPLDERCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRGKRNEFVPYKSKGARFRSGKDYVGELSVDLKRRLDSITSSQSSASSGFVEEKSLSDVEEEEASEELYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDPRLPLKWMAPETIFDRIYTIQSGVWSFGVLLWEIFSLGASPYPGVKIDEKFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPAFSELVEHLGNLLQANAQQDGKDYIVLPMSETLSMEEDSGLSLPTSPVSCMEEEEVCDPKFHYDNTAGISHYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDSQTDSGMVLASEELKTLEDRNKLSPSFGGMMPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYSSDEAGLLKLVDVAGHVDSGTTLRSSPV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 46 | N-linked (GlcNAc...) asparagine |
|
||
| 96 | N-linked (GlcNAc...) asparagine |
|
||
| 143 | N-linked (GlcNAc...) asparagine |
|
||
| 158 | N-linked (GlcNAc...) asparagine |
|
||
| 245 | N-linked (GlcNAc...) asparagine |
|
||
| 318 | N-linked (GlcNAc...) asparagine |
|
||
| 374 | N-linked (GlcNAc...) asparagine |
|
||
| 395 | N-linked (GlcNAc...) asparagine |
|
||
| 507 | N-linked (GlcNAc...) asparagine |
|
||
| 576 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Neurophilin interactions with VEGF and VEGFR | Rattus norvegicus |
| VEGF binds to VEGFR leading to receptor dimerization | Rattus norvegicus |
| VEGFA-VEGFR2 Pathway | Rattus norvegicus |
| VEGFR2 mediated cell proliferation | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13812 | adhesions of uterus | |
| DOID:1679 | cystitis | |
| DOID:2316 | brain ischemia | |
| DOID:5844 | myocardial infarction |
