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Histone deacetylase 1

Summary

UniProt ID

O09106

Gene Symbol

Hdac1

Organism

Mus musculus (house mouse)

External Links

GlyGen: O09106
PubChem: O09106
The O-GlcNAc Database: O09106

Annotation

Keyword

Acetylation
Biological rhythms
Chromatin regulator
Hydrolase
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Reference proteome
Repressor
S-nitrosylation
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

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GO Term
chromatin organization
endoderm development
positive regulation of cell population proliferation
epidermal cell differentiation
neuron differentiation
negative regulation of cell migration
hippocampus development
odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
oligodendrocyte differentiation

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GO Term
nucleus
cytoplasm
protein-containing complex
neuronal cell body
NuRD complex
transcription repressor complex
Sin3-type complex
cytosol
chromatin
heterochromatin

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GO Term
RNA polymerase II core promoter sequence-specific DNA binding
transcription corepressor binding
p53 binding
transcription corepressor activity
histone deacetylase activity
deacetylase activity
Krueppel-associated box domain binding
histone deacetylase binding
E-box binding
histone decrotonylase activity

Annotation information from UniProt.

Sequence

MAQTQGTKRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEFSDSDEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
349			G90659AW	GlyGen
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Deactivation of the beta-catenin transactivating complex	Mus musculus
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Mus musculus
Factors involved in megakaryocyte development and platelet production	Mus musculus
Formation of the beta-catenin:TCF transactivating complex	Mus musculus
G0 and Early G1	Mus musculus
HDACs deacetylate histones	Mus musculus
Notch-HLH transcription pathway	Mus musculus
RNA Polymerase I Transcription Initiation	Mus musculus
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Mus musculus
Regulation of MECP2 expression and activity	Mus musculus