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Histone deacetylase 1

Summary

UniProt ID

O09106

Gene Symbol

Hdac1

Organism

Mus musculus (house mouse)

External Links

GlyGen: O09106
PubChem: O09106

Annotation

Keyword

Acetylation
Biological rhythms
Chromatin regulator
Hydrolase
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Reference proteome
Repressor
S-nitrosylation
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

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GO Term
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
endoderm development
circadian rhythm
positive regulation of cell population proliferation
epidermal cell differentiation
negative regulation of cell migration
odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
oligodendrocyte differentiation

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GO Term
nucleoplasm
cytosol
perinuclear region of cytoplasm
chromatin
heterochromatin
nucleus
cytoplasm
protein-containing complex
neuronal cell body
transcription regulator complex

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GO Term
chromatin binding
deacetylase activity
Krueppel-associated box domain binding
histone decrotonylase activity
transcription cis-regulatory region binding
transcription corepressor binding
p53 binding
DNA binding
transcription corepressor activity
histone deacetylase activity

Annotation information from UniProt.

Sequence

MAQTQGTKRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEFSDSDEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
349			G90659AW	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Deactivation of the beta-catenin transactivating complex	Mus musculus
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Mus musculus
Factors involved in megakaryocyte development and platelet production	Mus musculus
Formation of the beta-catenin:TCF transactivating complex	Mus musculus
G0 and Early G1	Mus musculus
HDACs deacetylate histones	Mus musculus
Notch-HLH transcription pathway	Mus musculus
RNA Polymerase I Transcription Initiation	Mus musculus
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Mus musculus
Regulation of MECP2 expression and activity	Mus musculus