Fucose-1-phosphate guanylyltransferase

Summary
UniProt ID
O14772
Gene Symbol
  • FPGT
  • GFPP
Organism
Homo sapiens (human)
External Links
GlyGen
O14772
PubChem
O14772
The Human Metabolome Database
HMDBP00254
The O-GlcNAc Database
O14772
Annotation
Keyword
  • Alternative splicing
  • Cytoplasm
  • GTP-binding
  • Nucleotidyltransferase
  • Reference proteome
Gene Ontology (GO)
Displaying 1 entry
GO Term
fucose metabolic process
Displaying all 2 entries
GO Term
cytoplasm
cytosol
Sequence
MRAVRRGLREGGAMAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADEKQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSFTILLIHSGGYSQRLPNASALGKIFTALPLGNPIYQMLELKLAMYIDFPLNMNPGILVTCADDIELYSIGEFEFIRFDKPGFTALAHPSSLTIGTTHGVFVLDPFDDLKHRDLEYRSCHRFLHKPSIEKMYQFNAVCRPGNFCQQDFAGGDIADLKLDSDYVYTDSLFYMDHKSAKMLLAFYEKIGTLSCEIDAYGDFLQALGPGATVEYTRNTSNVIKEESELVEMRQRIFHLLKGTSLNVVVLNNSKFYHIGTTEEYLFYFTSDNSLKSELGLQSITFSIFPDIPECSGKTSCIIQSILDSRCSVAPGSVVEYSRLGPDVSVGENCIISGSYILTKAALPAHSFVCSLSLKMNRCLKYATMAFGVQDNLKKSVKTLSDIKLLQFFGVCFLSCLDVWNLKVTEELFSGNKTCLSLWTARIFPVCSSLSDSVITSLKMLNAVKNKSAFSLNSYKLLSIEEMLIYKDVEDMITYREQIFLEISLKSSLM
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
GDP-fucose biosynthesis Homo sapiens
Disease
Displaying all 7 entries
DO ID Disease Name Source
DOID:4450 renal cell carcinoma
DOID:4451 renal carcinoma
DOID:4464 collecting duct carcinoma
DOID:4465 papillary renal cell carcinoma
DOID:4467 clear cell renal cell carcinoma
DOID:4471 chromophobe renal cell carcinoma
DOID:4473 sarcomatoid renal cell carcinoma

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024