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MIRAGE
Tumor necrosis factor ligand superfamily member 11
Summary
- UniProt ID
- O14788
- Gene Symbol
-
- OPGL
- RANKL
- TNFSF11
- TRANCE
- Gene ID
- 8600
- Organism
- Homo sapiens (human)
External Links
- PubChem
- O14788
- The Human Metabolome Database
- HMDBP02409
- Re-Glyco
- O14788
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cytokine
- Cytoplasm
- Developmental protein
- Differentiation
- Disease variant
- Glycoprotein
- Osteopetrosis
- Receptor
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| tumor necrosis factor receptor superfamily binding |
| cytokine activity |
| tumor necrosis factor receptor binding |
| identical protein binding |
Sequence
MRRASRDYTKYLRGSEEMGGGPGAPHEGPLHAPPPPAPHQPPAASRSMFVALLGLGLGQVVCSVALFFYFRAQMDPNRISEDGTHCIYRILRLHENADFQDTTLESQDTKLIPDSCRRIKQAFQGAVQKELQHIVGSQHIRAEKAMVDGSWLDLAKRSKLEAQPFAHLTINATDIPSGSHKVSLSSWYHDRGWAKISNMTFSNGKLIVNQDGFYYLYANICFRHHETSGDLATEYLQLMVYVTKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSINVGGFFKLRSGEEISIEVSNPSLLDPDQDATYFGAFKVRDID
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | Homo sapiens |
| TNFR2 non-canonical NF-kB pathway | Homo sapiens |
| TNFs bind their physiological receptors | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110943 | autosomal recessive osteopetrosis 2 | |
| DOID:11476 | osteoporosis |
